Fig. 3

A Terbinafine treatment led to the accumulation of 4, 4′-diapophytoene. B Ligand binding residues prediction by for CrtN; predicted ligand binding residues are shown as blue sticks. C Domain boundary prediction for CrtN; the model was colored according to the predicted domains. The putative binding mode of terbinafine into the predicted active site of CrtN receptor in 2D (D) and 3D structure (E). The blue and cyan shadows of the ligand and active site amino acids, respectively, indicated strong hydrophobic/hydrophilic interactions. Data shown represent the mean ± standard of error from triplicate experiments. Using Student’s t test, P value < 0.05 was considered statistically significant