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Table 1 Clinical and microbiological characteristics of patients with hvKp or cKp (n = 86)

From: Genomic insights into virulence factors affecting tissue-invasive Klebsiella pneumoniae infection

 

hvKp (n = 19)

cKp (n = 67)

p value

Age (years), median (IQR)

74 (68–75)

78 (68–84)

0.064

Male, n (%)

14 (74)

38 (57)

0.18

Comorbidity, n (%)

   

 Diabetes mellitus

8 (42)

22 (33)

0.45

 Malignancy

0 (0)

24 (36)

0.002

 Immunocompromised conditions

2 (11)

9 (13)

0.54

 Liver cirrhosis

3 (16)

1 (1)

0.032

 Chronic kidney disease

2 (11)

6 (9)

0.57

Charlson index, median (IQR)

2 (1–3)

3 (2–5)

0.052

Community acquired, n (%)

11 (58)

34 (51)

0.58

Admitted to ICU, n (%)

3 (16)

8 (12)

0.46

In-hospital mortality, n (%)

6 (32)

16 (24)

0.34

Microbiological profile, n (%)

   

 Positive string test

16 (84)

38 (57)

0.029

 O1*

17 (89)

36 (54)

0.005

 O2*

1 (5)

21 (31)

0.016

 O3

1 (5)

8 (12)

0.36

 K1

8 (42)

5 (7)

0.001

 K2

6 (32)

22 (33)

0.92

 Aerobactin

16 (84)

36 (54)

0.016

 Yersiniabactin

12 (63)

30 (45)

0.16

 Salmochelin

14 (74)

35 (52)

0.096

 Colibactin

7 (37)

16 (24)

0.26

 rmpA

17 (89)

34 (51)

0.002

 rmpA2

10 (53)

32 (48)

0.71

  1. hvKp, hypervirulent K. pneumoniae; cKp, classical K. pneumoniae; IQR, interquartile range
  2. *The three O1/O2v2 strains in cKp