From: Genomic insights into virulence factors affecting tissue-invasive Klebsiella pneumoniae infection
hvKp (n = 19) | cKp (n = 67) | p value | |
---|---|---|---|
Age (years), median (IQR) | 74 (68–75) | 78 (68–84) | 0.064 |
Male, n (%) | 14 (74) | 38 (57) | 0.18 |
Comorbidity, n (%) | |||
Diabetes mellitus | 8 (42) | 22 (33) | 0.45 |
Malignancy | 0 (0) | 24 (36) | 0.002 |
Immunocompromised conditions | 2 (11) | 9 (13) | 0.54 |
Liver cirrhosis | 3 (16) | 1 (1) | 0.032 |
Chronic kidney disease | 2 (11) | 6 (9) | 0.57 |
Charlson index, median (IQR) | 2 (1–3) | 3 (2–5) | 0.052 |
Community acquired, n (%) | 11 (58) | 34 (51) | 0.58 |
Admitted to ICU, n (%) | 3 (16) | 8 (12) | 0.46 |
In-hospital mortality, n (%) | 6 (32) | 16 (24) | 0.34 |
Microbiological profile, n (%) | |||
Positive string test | 16 (84) | 38 (57) | 0.029 |
O1* | 17 (89) | 36 (54) | 0.005 |
O2* | 1 (5) | 21 (31) | 0.016 |
O3 | 1 (5) | 8 (12) | 0.36 |
K1 | 8 (42) | 5 (7) | 0.001 |
K2 | 6 (32) | 22 (33) | 0.92 |
Aerobactin | 16 (84) | 36 (54) | 0.016 |
Yersiniabactin | 12 (63) | 30 (45) | 0.16 |
Salmochelin | 14 (74) | 35 (52) | 0.096 |
Colibactin | 7 (37) | 16 (24) | 0.26 |
rmpA | 17 (89) | 34 (51) | 0.002 |
rmpA2 | 10 (53) | 32 (48) | 0.71 |