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Fig. 3 | Annals of Clinical Microbiology and Antimicrobials

Fig. 3

From: Antibiotic resistance modifying ability of phytoextracts in anthrax biological agent Bacillus anthracis and emerging superbugs: a review of synergistic mechanisms

Fig. 3

Mechanisms of action of phytochemical synergists in reversing antibiotic resistance in bacteria. Plant-derived compounds are capable of modifying the course of drug resistance in bacteria by interacting with antibiotic binding target sites/receptors, inhibition of antibiotic degrading enzymes, increasing cell membrane permeability to antibiotic molecules and disruption of drug extruding efflux pumps like MFS: Major Facilitator Super-family, SMR: Small Multidrug Resistance super-family, MATE: Multidrug and Aoxic Compound Extrusion super-family, RND: Resistance-nodulation-cell Division super-family, ABC: ATP-binding Cassette super-family. ATP: Adenosine triphosphate, ADP: Adenosine diphosphate, H + : Hydrogen, EGCG: Epigallocatechin gallate, PBP2a: Penicillin-binding protein 2a

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Annals of Clinical Microbiology and Antimicrobials

ISSN: 1476-0711

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