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Table 1 Characteristics of included studies

From: Evaluation of Xpert GBS assay and Xpert GBS LB assay for detection of Streptococcus agalactiae

Author Year Country Study design Reference standard Detection method Sample type Sample source The timing of specimen collection Pregnancy time The number of sample TP FP FN TN
El Helali 2009 French Prospective Culturea Xpert GBS Vaginal Hospital Intrapartum ≥ 35 weeks 863 135 3 2 723
Bourgeois-Nicolaos 2013 French Prospective Direct cultureb Xpert GBS Amniotic fluid Hospital Intrapartum ≥ 37 weeks 139 10 2 1 126
Park 2013 South Korea Prospective Enrichment culturec Xpert GBS Vaginal-rectal Hospital Antepartum 35–39 weeks 175 13 7 2 153
Buchan 2014 America Prospective Enrichment culturec Xpert GBS LB Vaginal-rectal Hospital Antepartum 35–37 weeks 826 189 48 2 587
Buchan 2014 America Prospective Enrichment culturec Xpert GBS Vaginal-rectal Hospital Antepartum 35–37 weeks 505 96 15 16 378
Gouve 2016 Brazil Prospective Enrichment culturec Xpert GBS Vaginal-rectal Hospital Antepartum 35–37 weeks 336 55 14 9 258
Helmig 2017 Denmark Prospective Enrichment culturec Xpert GBS Vaginal-rectal Hospital Intrapartum ≥ 34 weeks 105 25 2 0 78
Rabaan 2017 Saudi Arabia Prospective Enrichment culturec Xpert GBS Vaginal-rectal Clinics Antepartum 35–37 weeks 554 139 44 0 371
Plainvert 2017 France Prospective Direct cultureb Xpert GBS Vaginal Hospitals Intrapartum > 34 weeks 516 238 56 44 178
Said 2018 South Africa Prospective Direct cultureb Xpert GBS Vaginal-rectal Hospitals Antepartum 26 and 37 weeks 279 61 5 9 204
Shin 2019 America Prospective Enrichment culturec Xpert GBS LB Vaginal-rectal Hospitals and clinics Antepartum 35–37 weeks 500 107 40 1 352
Vieira 2019 Brazil Prospective Direct cultureb Xpert GBS Vaginal-rectal Hospitals Intrapartum ≥ 24 weeks 220 21 45 13 141
Tickler 2019 America Prospective Enrichment culturec Xpert GBS LB Vaginal or Vaginal/rectal Hospitals Unclear Unclear 145 40 0 4 101
Tickler 2019 America Prospective Enrichment culturec Xpert GBS LB Vaginal or Vaginal/rectal Hospitals Unclear Unclear 210 194 0 16 0
Tickler 2019 America Prospective Enrichment culturec Xpert GBS Vaginal-rectal Hospitals Unclear Unclear 100 0 0 0 100
Tickler 2019 America Prospective Enrichment culturec Xpert GBS LB Vaginal-rectal Hospitals Unclear Unclear 100 0 0 0 100
Tickler 2019 America Prospective Enrichment culturec Xpert GBS LB Vaginal-rectal Hospitals Unclear Unclear 300 54 17 0 229
Tickler 2019 America Retrospective Enrichment culturec Xpert GBS Vaginal-rectal Hospitals Unclear Unclear 150 149 0 1 0
Choera 2020 America Prospective Enrichment culturec&Revogene GBS LB assay Xpert GBS LB Vaginal-rectal Hospitals Intrapartum 35–37 weeks 250 50 1 1 198
  1. aIn this research, it refers to that specimens were cultured directly on blood agar plate and were subsequently placed in a broth medium
  2. bIn this research, it refers to that specimens were cultured directly on blood agar plate without enrichment
  3. cIn this research, it refers to that specimens were incubated to enrichment broth before detection