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Table 2 Antifungal susceptibility testing results (ATB Fungus 3) of 378 Candida [n (%)]

From: Epidemiology, species distribution, and outcome of nosocomial Candida spp. bloodstream infection in Shanghai: an 11-year retrospective analysis in a tertiary care hospital

 

C.albicans (n = 134)

C.parapsilosis (n = 86)

C.tropicalis (n = 67)

C.glabrata (n = 47)

C.krusei (n = 5)

C.sake (n = 8)

C.guilliermondii

(n = 19)

Other Candida spp. (n = 12)

Total(n = 378)

Fluconazole

S

126 (94)

77(89.5)

35 (52.2)

0 (0)

0 (0)

8(100)

13 (68.4)

9 (75.0)

268 (70.9)

SDD

1 (0.8)

6 (7.0)

3 (4.5)

44(93.6)

0 (0)

0 (0)

0 (0)

0 (0)

54 (14.3)

R

7 (5.2)

3 (3.5)

29 (43.3)

3 (6.4)

5 (100)

0 (0)

6 (31.6)

3 (25.0)

56 (14.8)

Itraconazole

S

110 (82.1)

75 (87.2)

25 (37.3)

0 (0)

0 (0)

8 (100)

6 (31.6)

9 (75.0)

233 (61.6)

SDD

6 (4.5)

7 (8.1)

4 (6.0)

40 (85.1)

2 (40.0)

0 (0)

7 (36.8)

0 (0)

66 (17.5)

R

18 (13.4)

4 (4.7)

38 (56.7)

7 (14.9)

3 (60.0)

0 (0)

6 (31.6)

3 (25.0)

79 (20.9)

Voriconazole

S

125 (93.3)

79 (91.9)

41 (61.2)

45 (95.8)

4 (80.0)

8 (100)

12 (63.2)

11 (91.7)

325 (86.0)

SDD

0 (0)

2 (2.3)

2 (3.0)

1 (2.1)

1 (2.0)

0 (0)

3 (15.8)

0 (0)

9 (2.4)

R

9 (6.7)

5 (5.8)

24 (35.8)

1 (2.1)

0 (0)

0 (0)

4 (21.0)

1 (8.3)

44 (11.6)

Amphotericin B

S

133 (99.3)

83 (96.5)

67 (100)

47 (100)

5 (100)

8 (100)

18 (94.7)

11 (91.7)

372 (98.4)

R

1 (0.7)

3 (3.5)

0 (0)

0 (0)

0 (0)

0 (0)

1 (5.3)

1 (8.3)

6 (1.6)

Flucytosine

S

132 (98.5)

85 (98.8)

65 (97.0)

46 (97.9)

1 (20.0)

8 (100)

9 (47.4)

12 (100)

358 (94.7)

R

2 (1.5)

1 (1.2)

2 (3.0)

1 (2.1)

4 (80.0)

0 (0)

10 (52.6)

0 (0)

20 (5.3)

  1. 15 Candida spp. isolates did not have a susceptibility test, C. albicans (7), C. parapsilosis (2), C. tropicalis (2), and glabrata, theae, gum, haemulonii each
  2. R resistance, S susceptible, SDD susceptible dose dependence