Molecular characteristics of antibiotic-resistant Escherichia coli and Klebsiella pneumoniae strains isolated from hospitalized patients in Tehran, Iran

Table 3 MIC and molecular features related to NDM-producing and colistin-resistant K. pneumoniae isolates

Isolates	MIC (µg/mL)							ESBL genes	MBL genes	Sensitivity to antibiotic
Isolates	CIP	CTX	CEP	CAZ	IMI	MER	CO	ESBL genes	MBL genes	Sensitivity to antibiotic
K37	128	64	64	64	128	128	128	CTX-M, TEM, SHV	–	FOS
K38	128	64	64	64	128	128	64	CTX-M, TEM	–	TGC, FOS
K50	256	512	512	512	8	8	64	CTX-M, TEM, SHV	–	TGC, FOS
K52	256	512	512	512	8	16	4	CTX-M	–	TGC
K53	128	512	512	512	8	8	4	CTX-M, SHV	–	TGC
K54^a	256	128	128	128	32	16	16	CTX-M, TEM	–	–
K57	256	16	16	16	16	16	4	CTX-M, SHV	–	TGC
K83	128	32	32	32	32	8	128	CTX-M, TEM, SHV	–	TGC, FOS
K101	128	512	512	512	64	64	128	CTX-M,TEM, SHV	–	TGC, FOS
K111	16	128	128	128	8	16	4	CTX-M, TEM	–	TGE, FOS
K130	128	512	512	512	8	32	8	CTX-M. TEM, SHV	–	TGC
K134	16	64	64	64	8	8	4	CTX-M, TEM	–	FOS, TGE
K136	128	512	64	512	16	16	8	TEM, SHV	–	MER
K148	16	8	16	16	16	32	4	TEM	–	TGE
K151	16	16	16	16	4	4	4	TEM	–	DOR,TGE
K158	8	16	16	16	4	4	4	TEM	–	DOR, TGE, FOS
K36	128	32	32	32	128	128	1	CTX-M, TEM, SHV	NDM-1	CO
K72	128	32	32	32	32	64	1	CTX-M, TEM, SHV	NDM-1	CO, TGC, FOS
K120	128	512	512	512	16	16	1	CTX-M, TEM, SHV	NDM-1	CO
K161	128	32	32	32	128	32	1	CTX-M, TEM, SHV	NDM-6	CO
K162	64	64	64	64	64	64	1	CTX-M, TEM, SHV	NDM-6	CO
K165	128	64	64	64	64	64	1	CTX-M, TEM, SHV	NDM-6	CO

CIP ciprofloxacin, CTX cefotaxime, CAZ ceftazidime, FEP cefepime, TGC tigecycline, DOR doripenem, ETP ertapenem, IMI imipenem, MEM meropenem, FOT fosfomycin/trometamol, CO colistin
^aPandrug-resistant

ISSN: 1476-0711