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Table 3 Antimicrobial susceptibility patterns of STEC isolates

From: Characterization of antimicrobial susceptibility, extended-spectrum β-lactamase genes and phylogenetic groups of Shigatoxin producing Escherichia coli isolated from patients with diarrhea in Iran

Antibiotic

Total (n = 174)

ESBL– (n = 103)

ESBL + (n = 71)

P-value

R No. (%)

I No. (%)

S No. (%)

R No. (%)

I No. (%)

S No. (%)

R No. (%)

I No. (%)

S No. (%)

Cefotaxime

77 (44.3)

3 (1.7)

94 (54.0)

7 (6.8)

2 (1.9)

94 (91.3)

70 (98.6)

1 (1.4)

< 0.001

Ceftazidime

49 (28.2)

20 (11.5)

105 (60.3)

5 (4.9)

3 (2.9)

95 (92.2)

44 (62.0)

17 (23.9)

10 (14.1)

< 0.001

Piperacillin-tazo

1 (0.6)

11 (6.3)

162 (93.1)

5 (4.9)

98 (95.1)

1 (1.4)

6 (8.2)

64 (90.1)

0.298

Ertapenem

1 (0.6)

173 (99.4)

1 (1.0)

102 (99.0)

71 (100)

0.405

Imipenem

1 (0.6)

173 (99.4)

1 (1.0)

102 (99.0)

71 (100)

0.405

Ciprofloxacin

44 (25.3)

10 (5.74)

120 (69.0)

14 (13.6)

4 (3.9)

85 (82.5)

30 (42.4)

6 (8.2)

35 (49.4)

< 0.001

Levofloxacin

42 (24.1)

3 (1.7)

129 (74.2)

10 (9.7)

2 (1.94)

91 (88. 4)

32 (45.1)

1 (1.4)

38 (53.5)

< 0.001

Amikacin

1 (0.6)

6 (3.4)

167 (96.0)

3 (2.9)

100 (97.1)

1 (1.4)

3 (4.2)

67 (94.4)

0.429

Tetracyclines

100 (57.5)

4 (2.3)

70 (40.2)

44 (42.7)

3 (2.9)

56 (54.4)

56 (78.9)

1 (1.4)

14 (19.7)

< 0.001

Ampicillin

119 (68.4)

5 (2.9)

50 (28.7)

49 (47.6)

5 (4.9)

49 (47.6)

70 (98.6)

1 (1.4)

< 0.001

Trimethoprim-sulfa

104 (59.8)

70 (40.2)

43 (41.7)

60 (58.3)

61 (85.9)

10 (14.1)

< 0.001

  1. R resistant, I intermediate, S sensitive, ESBL extended spectrum β-lactamase, STEC Shiga toxin‐producing Escherichia coli