Table 3 Antibiotic resistance genes and virulence genes of S. pneumoniae isolated from children with CAP
Variables | CC271 n (%) (n = 182) | Non-CC271 n (%) (n = 237) | Total n (%) (n = 419) | χ2 | P | |||
|---|---|---|---|---|---|---|---|---|
Positive | Negative | Positive | Negative | Positive | Negative | |||
erm(B) | 168 (92.3) | 14 (7.7) | 217 (91.6) | 20 (8.4) | 385 (91.9) | 34 (8.1) | 0.08 | 0.781 |
mef (A/E) | 156 (85.7) | 26 (14.3) | 83 (35.0) | 154 (65.0) | 239 (57.0) | 180 (43.0) | 107.96 |  < 0.001 |
tet (M) | 178 (97.8) | 4 (2.2) | 224 (94.9) | 13 (5.1) | 402 (95.9) | 17 (4.1) | 1.61 | 0.205 |
tet (K) | 0 (0.0) | 182 (100.0) | 3 (1.3) | 234 (98.7) | 3 (0.7) | 416 (99.3) | 0.26 | 0.180 |
tet (L) | 0 (0.0) | 182 (100.0) | 7 (3.0) | 230 (97.0) | 7 (1.7) | 412 (98.3) | 5.46 | 0.021 |
tet (O) | 3 (1.6) | 179 (98.4) | 7 (3.0) | 230 (97.0) | 10 (2.4) | 409 (97.6) | 0.29 | 0.586 |
ply | 171 (94.0) | 11 (6.0) | 211 (89.0) | 26 (11.0) | 382 (91.2) | 37 (8.8) | 3.10 | 0.078 |
lytA | 182 (100.0) | 0 (0.0) | 221 (93.2) | 16 (6.8) | 403 (96.2) | 16 (3.8) | 12.77 |  < 0.001 |
psaA | 8 (4.4) | 174 (95.6) | 7 (3.0) | 230 (97.0) | 15 (3.6) | 404 (96.4) | 0.62 | 0.431 |
pspA | 123 (67.6) | 59 (32.4) | 150 (63.3) | 87 (36.7) | 273 (65.2) | 146 (34.8) | 0.84 | 0.361 |
rlrA | 91 (50.0) | 91 (50.0) | 48 (20.3) | 189 (79.7) | 139 (33.2) | 280 (66.8) | 41.09 |  < 0.001 |
sipA | 154 (84.6) | 28 (15.4) | 32 (13.5) | 205 (86.5) | 186 (44.4) | 233 (55.6) | 210.89 |  < 0.001 |