Table 1 Antimicrobial susceptibility of S. pneumoniae isolated from children with CAP
Antibiotic | CC271 n (%) (n = 182) | Non-CC271 n (%) (n = 237) | Total n (%) (n = 419) | χ2 | P | |||
|---|---|---|---|---|---|---|---|---|
R | S | R | S | R | S | |||
Penicillin Parenterala | 5 (2.7) | 177 (97.3) | 1 (0.4) | 236 (99.6) | 6 (1.5) | 413 (98.5) | 2.47 | 0.116 |
Vancomycin | 0 (0.0) | 182 (100.0) | 0 (0.0) | 237 (100.0) | 0 (0.0) | 419 (100.0) | – | – |
Erythromycin | 175 (96.2) | 7 (3.8) | 220 (92.8) | 17 (7.2) | 395 (94.3) | 24 (5.7) | 2.11 | 0.146 |
Levofloxacin | 2 (1.1) | 180 (98.9) | 2 (0.8) | 235 (99.2) | 415 (99.0) | 4 (1.0) | 0.00 | 1.000 |
Tetracycline | 169 (92.9) | 13 (7.1) | 200 (84.4) | 37 (15.6) | 368 (87.8) | 51 (12.2) | 7.03 | 0.008 |
Trimethoprim-sulfamethoxazole | 167 (91.8) | 15 (8.2) | 202 (85.2) | 35 (14.8) | 369 (88.1) | 50 (11.9) | 4.17 | 0.041 |
Linezolid | 15 (8.2) | 167 (91.8) | 20 (8.4) | 217 (91.6) | 35 (8.4) | 384 (91.6) | 0.01 | 0.942 |
Clindamycin | 177 (97.3) | 5 (2.7) | 220 (92.8) | 17 (7.2) | 397 (94.7) | 22 (5.3) | 4.05 | 0.044 |
Chloramphenicol | 7 (3.8) | 175 (96.2) | 14 (5.9) | 223 (94.1) | 21 (5.0) | 398 (95.0) | 0.92 | 0.338 |
Cefotaximea | 81 (44.5) | 101 (55.5) | 39 (16.5) | 198 (83.5) | 120 (28.6) | 299 (71.4) | 39.63 |  < 0.001 |