Table 1 Associated factors of BSIs by univariate analysis
Features | Without BSIs (n = 90) | BSIs (n = 87) | P-value |
|---|---|---|---|
Sex | 0.49 | ||
 Female (n = 84) | 45 (50.0) | 39 (44.8) | |
 Male (n = 93) | 45 (50.0) | 48 (55.2) | |
Age | 0.96 | ||
 < 53.5 years (n = 100) | 51 (56.7) | 49 (56.3) | |
 ≥ 53.5 years (n = 77) | 39 (43.3) | 38 (43.7) | |
 Obesity (n = 25)a | 10 (11.4) | 15 (17.6) | 0.24 |
 Smoking (n = 16) | 11 (12.2) | 5 (5.7) | 0.13 |
 Alcohol intake (n = 11) | 8 (8.9) | 3 (3.4) | 0.13 |
Comorbidities | |||
 CVD (n = 7) | 3 (3.3) | 4 (4.6) | 0.96 |
 CHD (n = 5) | 1 (1.1) | 4 (4.6) | 0.34 |
 Diabetes mellitus (n = 33) | 14 (15.6) | 19 (21.8) | 0.28 |
 Hypertension (n = 49) | 26 (28.9) | 23(26.4) | 0.72 |
 Osteoporosis (n = 20) | 9 (10.0) | 11 (12.6) | 0.58 |
 Bedridden (n = 2) | 0 (0.0) | 2 (2.3) | 0.24 |
 Previous hospitalization (n = 18) | 10 (11.1) | 8 (9.2) | 0.67 |
The severity of skin lesions | 0.08 | ||
 Mild (n = 12) | 9 (10.0) | 3 (3.4) | |
 Moderate (n = 31) | 20 (22.2) | 11 (12.6) | |
 Severe (n = 52) | 24 (26.7) | 28 (32.2) | |
 Extensive (n = 82) | 37 (41.1) | 45 (51.7) | |
Subtype of pemphigus | 0.51 | ||
 PV and PVeg (n = 143) | 71 (78.9) | 72 (82.8) | |
 PE and PF (n = 34) | 19 (21.1) | 15 (17.2) | |
Therapy | |||
 Antibiotics (n = 40) | 20 (22.2) | 20 (23.0) | 0.90 |
 Glucocorticoids (n = 129) | 65 (72.2) | 64 (73.6) | 0.84 |
 Immunosuppressive agent (n = 43) | 26 (28.9) | 17 (19.5) | 0.15 |
 Hypoalbuminemia (n = 21) | 7 (8.0) | 14 (16.3) | 0.09 |
Anti-Dsg1 autoantibodiesb |  < 0.001 | ||
 ≤ 124.2 IU/ml (n = 61) | 44 (50.6) | 17 (20.5) | |
 > 124.2 IU/ml (n = 109) | 43 (49.4) | 66 (79.5) | |
Anti-Dsg3 autoantibodiesc | 0.01 | ||
 ≤ 169.5 IU/ml (n = 93) | 56 (64.4) | 37 (44.6) | |
 > 169.5 IU/ml (n = 77) | 31 (35.6) | 46 (55.4) | |