|
Sex
|
0.49
|
|
Female (n = 84)
|
45 (50.0)
|
39 (44.8)
|
|
Male (n = 93)
|
45 (50.0)
|
48 (55.2)
|
|
Age
|
0.96
|
|
< 53.5 years (n = 100)
|
51 (56.7)
|
49 (56.3)
|
|
≥ 53.5 years (n = 77)
|
39 (43.3)
|
38 (43.7)
|
|
Obesity (n = 25)a
|
10 (11.4)
|
15 (17.6)
|
0.24
|
|
Smoking (n = 16)
|
11 (12.2)
|
5 (5.7)
|
0.13
|
|
Alcohol intake (n = 11)
|
8 (8.9)
|
3 (3.4)
|
0.13
|
|
Comorbidities
|
|
CVD (n = 7)
|
3 (3.3)
|
4 (4.6)
|
0.96
|
|
CHD (n = 5)
|
1 (1.1)
|
4 (4.6)
|
0.34
|
|
Diabetes mellitus (n = 33)
|
14 (15.6)
|
19 (21.8)
|
0.28
|
|
Hypertension (n = 49)
|
26 (28.9)
|
23(26.4)
|
0.72
|
|
Osteoporosis (n = 20)
|
9 (10.0)
|
11 (12.6)
|
0.58
|
|
Bedridden (n = 2)
|
0 (0.0)
|
2 (2.3)
|
0.24
|
|
Previous hospitalization (n = 18)
|
10 (11.1)
|
8 (9.2)
|
0.67
|
|
The severity of skin lesions
|
0.08
|
|
Mild (n = 12)
|
9 (10.0)
|
3 (3.4)
|
|
Moderate (n = 31)
|
20 (22.2)
|
11 (12.6)
|
|
Severe (n = 52)
|
24 (26.7)
|
28 (32.2)
|
|
Extensive (n = 82)
|
37 (41.1)
|
45 (51.7)
|
|
Subtype of pemphigus
|
0.51
|
|
PV and PVeg (n = 143)
|
71 (78.9)
|
72 (82.8)
|
|
PE and PF (n = 34)
|
19 (21.1)
|
15 (17.2)
|
|
Therapy
|
|
Antibiotics (n = 40)
|
20 (22.2)
|
20 (23.0)
|
0.90
|
|
Glucocorticoids (n = 129)
|
65 (72.2)
|
64 (73.6)
|
0.84
|
|
Immunosuppressive agent (n = 43)
|
26 (28.9)
|
17 (19.5)
|
0.15
|
|
Hypoalbuminemia (n = 21)
|
7 (8.0)
|
14 (16.3)
|
0.09
|
|
Anti-Dsg1 autoantibodiesb
|
< 0.001
|
|
≤ 124.2 IU/ml (n = 61)
|
44 (50.6)
|
17 (20.5)
|
|
> 124.2 IU/ml (n = 109)
|
43 (49.4)
|
66 (79.5)
|
|
Anti-Dsg3 autoantibodiesc
|
0.01
|
|
≤ 169.5 IU/ml (n = 93)
|
56 (64.4)
|
37 (44.6)
|
|
> 169.5 IU/ml (n = 77)
|
31 (35.6)
|
46 (55.4)
|
