TY - JOUR AU - Lotte, Romain AU - Chevalier, Alicia AU - Dantas, Sabine AU - Degand, Nicolas AU - Gaudart, Alice AU - Rörhlich, Pierre-Simon AU - Boyer, Laurent AU - Rodriguez-Nava, Veronica AU - Del Giudice, Pascal AU - Ruimy, Raymond PY - 2020 DA - 2020/08/20 TI - Nocardia takedensis: a newly recognized pathogen responsible for skin and soft tissue infections JO - Annals of Clinical Microbiology and Antimicrobials SP - 38 VL - 19 IS - 1 AB - Nocardia takedensis was first isolated in 2005, from soil in Japan. We report here two cases of lymphangitis in France (2012–2017) caused by N. takedensis both occurring after skin injury while gardening, which enabled its inoculation. The two patients were immunocompromised and successfully treated by an antimicrobial agent active on the isolated strain, trimethoprim-sulfamethoxazole and amoxicillin-clavulanic acid for patient one and patient two, respectively. Our study along with previous ones supports the idea of a newly recognized cutaneous opportunistic pathogen and reinforces the recommendation of using gloves during soil exposure for immunocompromised patients. Lastly, according to data found in the literature, we would recommend trimethoprim-sulfamethoxazole as an efficient empirical antibiotic therapy in case of cutaneous infection caused by N. takedensis. SN - 1476-0711 UR - https://doi.org/10.1186/s12941-020-00379-7 DO - 10.1186/s12941-020-00379-7 ID - Lotte2020 ER -