Table 3 Resistome analysis of characterized carbapenem-resistant K. pneumoniae isolates from Puglia, Southern Italy

Aminoglycoside

aac(3)-IIa-

c2

c2

c2

c2

c2

aac(6′)-Ib

b-cr

b6

b-cr

b-p

b-cr

aph(3′)-Ia

a1

aph(3′′)-Ib

2

2

2

2

2

aph(6)-Id

1

1

1

1

1

β-lactams

bla_CTX-M-

15

15

15

15

bla_SHV-

28

55

28

28

1

1

bla_OXA-

1

1,9

1

9

bla_VIM-

1

1

bla_TEM-

1

1

1

1

1

1

bla_KPC-

3

3

3

3

3

Fluoroquinolones

gyrA

9

9

9

9

9

1

gyrB

1

1

1

1

1

1

parC

25

25

25

25

25

25

25

parE

1

1

1

1

1

1

1

qnr

B1

B1

B1

B1

S1

Efflux pumps

acrA

114

114

114

114

114

23

12

acrB

41

41

41

41

41

27

acrR

1

1

1

2

marA

1

1

1

1

1

1

5

marR

1

1

1

1

1

10

2

soxS

1

1

1

1

1

2

6

soxR

1

1

1

1

1

2

1

ramA

2

2

2

2

6

7

ramR

14

rob

3

3

3

3

3

3

1

sdiA

2

2

2

2

2

1

2

fis

1

1

1

1

1

1

1

envR

20

20

20

20

20

3

2

oqxA

136

136

136

136

136

24

12

oqxB

156

156

156

156

156

26

12

oqxR

4

4

4

4

4

15

4

rarA

20

20

20

20

20

14

8

Plasmid replicon types^b

IncFIA(HI1)

Χ

Χ

Χ

Χ

IncFIB

Χ

Χ

IncFIB(K)

Χ

Χ

Χ

Χ

IncFIB(Mar)

Χ

IncFIB(pQil)

Χ

Χ

IncFII

Χ

Χ

IncFII(K)

Χ

Χ

Χ

Χ

Χ

Χ

IncN

Χ

IncQ1

Χ

Χ

IncR

Χ

Χ

Χ

Χ

ColRNAI

Χ

Χ

Χ

Χ

Col440II

Χ

Χ