Table 2 Phenotypic and genotypic characteristics of colistin resistant strains
Isolate number | Isolate | Source | Colistin MIC by broth microdilution (µg/mL) | E-test | ST | OXA-48 | NDM-1 | mcr-1 | mcr-2 | mgr-B |
|---|---|---|---|---|---|---|---|---|---|---|
1 | E. coli | Blood | 4 | 0.75 | − | + | − | − | ||
2 | E. coli | Blood | 16 | 8 | − | − | − | − | Unobtainable | |
3 | E. coli | Pus | 4 | 3 | − | + | + | − | ||
4 | K. pneumoniae | Pus | 32 | 8 | 383 | − | − | − | − | |
5 | K. pneumoniae | Blood | 4 | 4 | 101 | − | − | − | − | Unobtainable |
6 | K. pneumoniae | Pus | 4 | 2 | 16 | − | − | − | − | WT |
7 | E. coli | Wound | 8 | 4 | + | − | − | − | Unobtainable | |
8 | K. pneumoniae | Pus | 4 | 3 | 11 | + | − | − | − | |
9 | K. pneumoniae | Drain | 4 | 2 | 383 | − | − | − | − | |
10 | E. coli | Blood | 4 | 4 | − | − | − | − | WT | |
11 | K. pneumoniae | Blood | 4 | 3 | 11 | − | − | + | − | WT |
12 | K. pneumoniae | Throat | 8 | 4 | 101 | + | − | − | − | WT |
13 | K. pneumoniae | Blood | 4 | 3 | 1399 | − | − | − | − | WT |
14 | K. pneumoniae | Blood | 32 | 16 | 147 | + | − | − | − | WT |
15 | K. pneumoniae | Blood | 4 | 12 | 147 | − | − | − | − | WT |
16 | K. pneumoniae | Blood | 4 | 4 | 16 | − | − | − | − | |
17 | K. pneumoniae | Nephrostomy | 4 | 3 | 101 | − | + | − | − | |
18 | K. pneumoniae | CVP | 16 | 8 | 2193 | − | + | − | − | WT |
19 | E. coli | Blood | 32 | 8 | − | − | − | − | Unobtainable | |
20 | E. coli | Pus | 8 | 4 | − | − | − | − | Unobtainable | |
21 | K. pneumoniae | Blood | 32 | 16 | 37 | − | + | − | − | WT |
22 | K. pneumoniae | Chest tube | 32 | 24 | 101 | − | − | − | − | WT |
23 | K. pneumoniae | Oral | 32 | 16 | 22 | − | + | − | − | WT |
24 | K. pneumoniae | Blood | 32 | 8 | 383 | − | − | − | − | WT |
25 | K. pneumoniae | Blood | 4 | 8 | 101 | − | − | − | − | Unobtainable |
26 | E. coli | CVP | 8 | 2 | − | − | − | − | Unobtainable | |
27 | E. coli | Blood | 32 | 4 | + | − | − | − | ||
28 | E. coli | Blood | 16 | 4 | + | − | − | − | Unobtainable | |
29 | E. coli | Blood | 8 | 4 | − | − | − | − | Unobtainable | |
30 | E. coli | Blood | 16 | 12 | − | − | − | − | ||
31 | K. pneumoniae | Blood | 16 | 12 | 785 | − | + | − | − | |
32 | E. coli | Blood | 16 | 8 | − | − | − | − | WT | |
33 | K. pneumoniae | Blood | 32 | 16 | 101 | − | + | − | − | |
34 | E. coli | Pus | 32 | 8 | − | − | − | − | Unobtainable | |
35 | K. pneumoniae | Blood | 8 | 4 | 1399 | − | − | − | − | Missense |
36 | K. pneumoniae | Pus | 4 | 4 | 101 | − | − | − | − | |
37 | E. coli | Sputum | 8 | 3 | + | − | − | − | ||
38 | E. coli | Blood | 8 | 4 | + | − | − | − | ||
39 | E. coli | Blood | 16 | 4 | − | − | − | − | ||
40 | E. coli | Blood | 16 | 4 | − | − | − | − | Unobtainable |