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Fig. 7 | Annals of Clinical Microbiology and Antimicrobials

Fig. 7

From: Potential factors contributing to the poor antimicrobial efficacy of SAAP-148 in a rat wound infection model

Fig. 7

Antimicrobial activity of SAAP-148 against MRSA in different ex vivo models. Ex vivo models were inoculated with approximately 105 CFU/mL MRSA for 1 h and then exposed to 20 µL of PBS with or without 60 nmol SAAP-148 in PBS for 1 h. a The efficacy of SAAP-148 in four wound types, i.e. excision wounds, BWM, tape-stripped skin and intact. b The efficacy of SAAP-148 in BWMs of skin from three species, i.e. human, rat and mouse. Results are expressed as the LR. Data represent the mean of at least five independent experiments performed in triplicate. * indicates significant difference (*p < 0.05; **p < 0.01)

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