Fig. 4

The effectiveness of SAAP-148 over time. Ex vivo excision wound models were inoculated with approximately 10⁵ CFU/mL MRSA for 1 h and subsequently exposed to 60 nmol SAAP-148 in 20 µL of PBS for 1 h, 4 h, or 24 h. PBS was used as negative control. Results are expressed as the LR. Data represent the mean of six independent experiments performed in triplicate. * indicates significant difference (*p < 0.05; **p < 0.01) as compared to the LR at a 1 h or 4 h exposure period of SAAP-148