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Fig. 2 | Annals of Clinical Microbiology and Antimicrobials

Fig. 2

From: Potential factors contributing to the poor antimicrobial efficacy of SAAP-148 in a rat wound infection model

Fig. 2

Absorption and/or adsorption by wound dressings and its effect on the efficacy of SAAP-148. a 100 µL of SAAP-148 in PBS (76 nmol) were incubated with or without 1 cm2 of a wound dressing or low adhesive Parafilm for 1 h. Subsequently, the remaining volume of SAAP-148 containing solutions were determined. Results are expressed as the relative recovery of the solutions in percentages of control samples without a wound dressing. Data are shown as mean ± SD of six independent experiments. b In vitro killing of MRSA by 10 µL of SAAP-148 containing solutions that were remaining after incubation with or without Cuticell, Parafilm and Tegaderm film. PBS was used as negative control. Results are expressed as the LR. The mean of six independent experiments performed in triplicate is shown. * indicates significant difference (*p < 0.05; **p <0.01) compared to control samples

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