Evaluation of serological test of Zika in an endemic area of flavivirus in the Colombian Caribbean

Table 1 Evaluation of ZIKV virus test IgG/IgM

Patients groups	Samples (year collection)	Positive results of ZIKV test
Patients groups	Samples (year collection)	n	IgM	IgG
Tropical fever groups with no ZIKV circulation n = 30	Dengue (2012)	19	18	2
	Leptospira (2012)	2	1	1
	Malaria (2012)	3	1	1
	Hantavirus (2012)	3	2	1
	Chikungunya (2014)	3	1	0
	Total	30	23	5
Epidemic ZIKV group with ZIKV circulation n = 33	ZIKV PCR positive^a (2015–2016)	11	7	0
	ZIKV PCR negative with high clinical suspicious^b (2015–2016)	10	8	0
	ZIKV convalescent non-acute stage^c (2015–2016)	6	5	0
	High clinical suspicious patients convalescent stage^d (2015–2016)	6	5	0
	Total	33	25	0

^a+b Sera were analyzed using the qRT-PCR kit (Zika virus polyprotein gene, genesig^® Advanced kit, Primer design Ltd., UK), viral loads were between 0.155–195 virus/μl
^bZIKV PCR negative with high clinical suspicious of ZIKV
^cZIKV convalescent non-acute stage confirmed by PCR (range 4–11 months)
^dHigh suspicious clinical ZIKV patients in convalescent stage, no confirmed by PCR (range 3 weeks–7 months)

ISSN: 1476-0711