Skip to main content

Table 1 Patient characteristics (n = 156)

From: Detection of bacterial DNA from central venous catheter removed from patients by next generation sequencing: a preliminary clinical study

  Total Routine removal group CRI-suspected group P value
(n = 156) (n = 125) (n = 31)
Age, years (mean ± SD) 65.6 ± 10.8 65.3 ± 10.9 66.5 ± 10.3 0.645
Male, n (%) 114 (73.1%) 93 (74.4%) 21 (67.7%) 0.500
Underlying diseasea
 Malignancy 126 (80.8%) 101 (80.8%) 25 (80.6%) 1.000
 Hepatocellular carcinoma 49 (31.4%) 43 (34.4%) 6 (19.4%)
 Pancreatic cancer 24 (15.4%) 20 (16.0%) 4 (12.9%)
 Cholangiocarcinoma 11 (7.1%) 5 (4.0%) 6 (19.4%)
 Other cancers 42 (26.9%) 33 (26.4%) 9 (29.0%)
 Diabetes mellitus 40 (25.6%) 33 (26.4%) 7 (22.6%) 0.819
 Chronic hepatitis/liver cirrhosis 21 (13.5%) 18 (14.4%) 3 (9.7%) 0.769
 Chronic kidney disease 3 (1.9%) 2 (1.6%) 1 (3.2%) 0.488
 Other diseases 30 (19.2%) 24 (19.2%) 6 (19.4%) 1.000
 Immunosuppressive drug use (yes) 8 (5.1%) 6 (4.8%) 2 (6.5%) 0.659
 qSOFA score point (mean and range) 0.2 (0–3) 0.1 (0–1) 0.5 (0–3) < 0.001
 Body temperature, °C (mean ± SD) 36.8 ± 0.8 36.6 ± 0.5 37.7 ± 1.1 < 0.001
 Skin redness at the insertion site 5 (3.2%) 0 (0%) 5 (16.1%) < 0.001
Insertion site of CVC
 Jugular 148 (94.9%) 120 (96.0%) 28 (90.3%) 0.196
 Femoral 3 (1.9%) 2 (1.6%) 1 (3.2%) 0.488
 Peripherally inserted CVC 5 (3.2%) 3 (2.4%) 2 (6.5%) 0.259
Number of lumen
 3 103 (66.0%) 84 (67.2%) 19 (61.3%) 0.533
 2 48 (30.8%) 38 (30.4%) 10 (32.3%) 0.831
 1 5 (3.2%) 3 (2.4%) 2 (6.5%) 0.259
Primary purpose for CVC insertion
 Perioperative 141 (90.4%) 114 (91.2%) 27 (87.1%) 0.500
 Parenteral nutrition 9 (5.8%) 6 (4.8%) 3 (9.7%) 0.383
 Intensive care 6 (3.8%) 5 (4.0%) 1 (3.2%) 1.000
 Duration of catheterization, days (mean ± SD) 9.5 ± 9.0 9.0 ± 8.0 11.5 ± 12.2 0.600
 Antibiotic use during the catheterization 153 (98.1%) 123 (98.4%) 30 (96.8%) 0.488
 Antibiotic use after the removal 47 (30.1%) 22 (17.6%) 25 (80.6%) < 0.001
 Defervescence time from the catheter removal, day (mean ± SD) 0.8 ± 2.4 0.3 ± 0.6 3.4 ± 4.5 < 0.001
  1. Data are presented as the number (percentage) of patients
  2. aSome overlap exists