Table 3 Major clinical differences between eumycetoma and actinomycetoma: summary of key findings
From: Mycetoma: a clinical dilemma in resource limited settings
Characteristics | Eumycetoma | Actinomycetoma |
|---|---|---|
Affected body parts [1] | Usually hand, feet and other parts of arms and legs | Usually chest, abdomen and head |
Lesion [32] | Well encapsulated with a clear margin | Diffuse, no clear margin |
Disease progression [64] | Slow | More rapid and inflammatory |
Sinus morphology [1] | Proliferative, protuberant | Depressed, flat |
Sinuses [32] | Few | Many |
Bone invasion [32] | Delayed | Rapid |
Bone radiograph [32] | Fewer but larger cavities with clear margins | Numerous, small cavities with unclear margins |
Color and texture of grains | Different colors, but mostly white or black; coarse texture | Different colors but not black; fine texture |
Lymphatic spread [1] | Occassional | Frequent |
Drugs (e.g.) [49] | Antifungals (ketoconazole, voriconazole, posaconazole, etc.) | Antibiotics (sulfamethoxazole–trimethoprim, rifampicin, amikacin, etc.) |
Recurrence [1] | More | Less |