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Table 1 Reported cases of acute infectious purpura fulminans with Streptococcus pyogenes infection

From: Streptococcus pyogenes-purpura fulminans as an invasive form of group A streptococcal infection

Patient no

Sex

Age at onset

Underlying disease

Plasma activity of protein C (%)

Complications

Outcomes

Reports

 

Extremities

Neurological

1

M

2 months

No

NR

Shock, DIC

Death

NR

Death

Lloyd and Bolte [14]

2

M

4 months

No

6

Shock, DIC

Alive

All toes and 7 digits lost

No deficits

Dhodapkar et al. [15]

3

F

2.5 years

No

NR

Shock, DIC, ARDS, MOF

Alive

Preserved

Brain death

Daskalaki et al. [16]

4

M

3 years

No

13

Shock, DIC

Alive

Amputation

No deficits

Our case

5

M

5 years

No

60

Shock, DIC

Alive

Preserved

No deficits

Dhodapkar et al. [15]

6

M

7 years

No

NR

Shock, DIC

Alive

Amputation

NR

Davis et al. [17]

7

F

7 years

Chylothorax

NR

Shock, DIC, MOF

Alive

Amputation

NR

Cruz et al. [18]

8

F

8 years

JIA, TNFα-blocker

NR

Shock, DIC, Renal failure

Death

Amputation

Death

Renaud et al. [19]

9

F

10 years

JIA, TNFα-blocker

NR

Shock, DIC, ARDS

Alive

Amputation

NR

Lovell et al. [20]

10

M

50 years

No

Normal

Shock, DIC, Renal failure

Alive

Skin grafting

NR

Gupta [21]

11

F

62 years

Asplenia, NHL

NR

DIC

Death

NR

Death

Ward et al. [22]

12

F

72 years

No

NR

Shock, DIC

Alive

NR

NR

Ashokkumar et al. [23]

  1. DIC disseminated intravascular coagulation, ARDS acute respiratory distress syndrome, MOF multiple organ failure, JIA juvenile idiopathic arthritis, TNF tumor necrosis factor, NHL non-Hodgkin’s lymphoma, NR not recorded