Table 4 Empiric antimicrobial agents stratified by type of infection
Empiric antimicrobial therapy | Number (%) of patients | ||||||||
|---|---|---|---|---|---|---|---|---|---|
Infection type | |||||||||
VABP (N = 31) | Bacteremia (N = 22) | cUTI/AP (N = 18) | HABP (N = 16) | SWI (N = 16) | BTI (N = 9) | DWI (N = 7) | SBFI (N = 5) | All (N = 124) | |
No treatment | 0 | 1 (4.5%) | 4 (22.2%) | 1 (6.3%) | 3 (18.8%) | 2 (22.2%) | 1 (14.3%) | 0 | 12 (9.7%) |
No Gram-negative coverage | 0 | 0 | 1 (5.6%) | 0 | 1 (6.3%) | 0 | 0 | 0 | 2 (1.6%) |
Gram-negative therapy | 31 (100%) | 21 (%) | 13 (72.2%) | 15 (93.8%) | 12 (75%) | 7 (77.8%) | 6 (85.7%) | 5 (100%) | 110 (88.7%) |
Monotherapy | 13 (41.9%) | 10 (45.5%) | 12 (66.7%) | 8 (50.0%) | 11 (68.8%) | 2 (22.2%) | 4 (57.1%) | 3 (60.0%) | 63 (50.8%) |
Dual therapy | 9 (29.0%) | 8 (36.4%) | 1 (5.6%) | 5 (31.3%) | 1 (6.25%) | 4 (44.4%) | 2 (28.6%) | 2 (40.0%) | 32 (25.8%) |
Three drug combinations | 6 (19.4%) | 2 (9.1%) | 0 | 2 (12.5%) | 0 | 1 (11.1%) | 0 | 0 | 11 (8.9%) |
Four and more drug combinations | 3 (9.7%) | 1 (4.5%) | 0 | 0 | 0 | 0 | 0 | 0 | 4 (3.2%) |
Number active agents | |||||||||
No active agent | 20 (64.5%) | 15 (68.2%) | 7 (38.9%) | 13 (81.3%) | 6 (37.5%) | 5 (55.6%) | 5 (71.4%) | 4 (80.0%) | 75 (60.5%) |
One active agent | 9 (29.0%) | 5 (22.7%) | 6 (33.3%) | 2 (12.5%) | 6 (37.5%) | 2 (22.2%) | 1 (14.3%) | 1 (20.0%) | 32 (25.8%) |
Two active agents | 2 (6.45%) | 1 (4.5%) | 0 | 0 | 0 | 0 | 0 | 0 | 3 (2.4%) |