Comparison of nephrotoxicity of Colistin with Polymyxin B administered in currently recommended doses: a prospective study

Table 6 Subgroup analysis of reversal of Colistin nephrotoxicity

Subgroup	Nephrotoxicity		Difference	95% CI	P value
DM	Yes	No	0.13	− 0.21 to 0.46	0.478
DM	9 (81.8)	9 (69.2)	0.13	− 0.21 to 0.46	0.478
Baseline creatinine clearance (ml/min)	≥ 50	< 50	0.19	− 0.28 to 0.66	0.384
Baseline creatinine clearance (ml/min)	15 (78.9)	3 (60)	0.19	− 0.28 to 0.66	0.384
Age	≥ 65	< 65	0	− 0.35 to 0.35	1.000
Age	9 (75.0)	9 (75.0)	0	− 0.35 to 0.35	1.000
BMI	≥ 30	< 30	− 0.52	− 0.84 to (− 0.21)	0.064
BMI	8 (100)	10 (62.5)	− 0.52	− 0.84 to (− 0.21)	0.064
Total daily dose	≥ 300 mg	< 300 mg	0.05	− 0.34 to 0.44	0.795
Total daily dose	13 (76.5)	5 (71.4)	0.05	− 0.34 to 0.44	0.795

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