Skip to main content

Table 3 Primary and secondary outcomes

From: Comparison of nephrotoxicity of Colistin with Polymyxin B administered in currently recommended doses: a prospective study

Outcome

Number of patients (%)

P value

Colistin

(n = 61)

Polymyxin B

(n = 51)

Nephrotoxicity

24 (39.3)

6 (11.8)

0.001

RIFLE

All classes (R+I+F)

32 (52.4)

10 (19.6)

< 0.001

R

8 (13.1)

4 (7.8)

0.105

I

13 (21.3)

4 (7.8)

0.009

F

11 (18.0)

2 (3.9)

0.004

Secondary outcomes

Need for dialysis

9 (14.8)

1 (2.0)

0.018

Need for stopping medication

9 (14.8)

1 (2.0)

0.018

Onset of AKI (mean ± SD)

3.8 ± 0.8

4.2 ± 0.7

0.373

Duration of AKI (mean ± SD)

4.9 ± 3.1

5.0 ± 2.4

0.916

Reversal of nephrotoxicity, n (%)

18 (75.0)

5 (83.3)

0.666

  1. Data are presented as n (%), or mean ± SD