Skip to main content

Table 2 Patient characteristics in 2 groups

From: Comparison of nephrotoxicity of Colistin with Polymyxin B administered in currently recommended doses: a prospective study

Variable

Colistin

(n = 61)

Polymyxin B

(n = 51)

P value

Gender, male

39 (63.9)

36 (70.6)

0.456

Age (years)

64.3 ± 13.3

63.4 ± 17.1

0.769

Weight (kg)

73.2 ± 11.8

69.3 ± 13.4

0.106

BMI (kg/m2)

26.8 ± 4.3

25.0 ± 4.7

0.041

APACHE 2 score

20.8 ± 4.2

22.0 ± 4.6

0.167

Baseline creatinine clearance (ml/min)

60.8 ± 33.5

55.4 ± 31.6

0.382

DM

30 (49.2)

22 (43.1)

0.523

HTN

12 (19.7)

11 (21.6)

0.071

Use of vasopressors

39 (63.9)

28 (54.9)

0.381

Number of days of antibiotic use [median(IQR)]

7 (5–7)

7 (7–9)

0.221

Median daily dose (mg)

233.3 (150–300)

200 (180–240)

0.116

Site of infection

Lungs

28 (45.9)

38 (74.5)

0.002

Urine

19 (31.1)

0 (0)

< 0.001

Bloodstream

5 (8.2)

5 (9.8)

0.766

Abdomen

5 (8.2)

4 (7.8)

0.945

Others

4 (6.5)

4 (7.8)

0.792

Pathogens

Klebsiella

19 (31.1)

12 (23.5)

0.370

Pseudomonas

8 (13.1)

11 (21.6)

0.235

Acinetobacter

12 (19.7)

10 (19.6)

0.993

E. coli

4 (6.5)

1 (2)

0.241

No growth

18 (29.5)

17 (33.3)

0.664

  1. Data are presented as n (%), mean ± SD or median (IQR)