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Table 1 Reported cases of antibiotic-associated hemorrhagic colitis due to the second-line therapy for Helicobacter pylori eradication

From: Second-line therapy for Helicobacter pylori eradication causing antibiotic-associated hemorrhagic colitis

Age

Gender

Symptoms

Onset

First-line therapy

Second-line therapy

Fecal bacterial culture

DLST

References

58

F

Abdominal pain, bloody diarrhea

8 days after starting eradication

CAM + AMPC + RPZ

MNZ 500 mg + AMPC 1500 mg + RPZ 20 mg

Pathogenic bacteria was not detected

Not described

#12

54

M

Abdominal pain, bloody diarrhea

7 days after starting eradication

CAM + AMPC + RPZ

MNZ 500 mg + AMPC 1500 mg + RPZ 20 mg

Pathogenic bacteria was not detected

Not described

#12

59

F

Abdominal pain, bloody diarrhea

9 days after starting eradication

CAM + AMPC + RPZ

MNZ 500 mg + AMPC 1500 mg + RPZ 20 mg

Pathogenic bacteria was not detected

Not described

#12

60

F

Abdominal pain, bloody diarrhea

9 days after starting eradication

CAM + AMPC + PPI

MNZ + AMPC + PPI

Klebsiella oxytoca

Not described

#13

50

M

Abdominal pain, hematochezia

6 days after starting eradication

CAM + AMPC + PPI

MNZ + AMPC + PPI

Not described

Not described

#13

65

F

Abdominal pain, hematochezia

8 days after starting eradication

CAM 800 mg + AMPC 1500 mg + LPZ 60 mg

MNZ 500 mg + AMPC 1500 mg + Vonoprazan 40 mg

Klebsiella oxytoca

Positive for both AMPC and MNZ

Present case

  1. CAM clarithromycin, AMPC amoxicillin, MNZ metronidazole, RPZ rabeprazole, LPZ lansoprazole, PPI proton pump inhibitor