Fig. 8
From: A pre-therapeutic coating for medical devices that prevents the attachment of Candida albicans
Filastatin prevents the attachment of C. albicans under flow conditions. a Schematic of the interdigitated gold microelectrodes for sensing impedance upon C. albicans attachment. b Schematic of the assembly of electron impedance spectroscopy (EIS) device in the microfluidic chamber that mimics physiological flow of bodily fluids. c Normalized impedance ratio results for C. albicans in SC + 0.15% dextrose and 50 µM Filastatin at 4 kHz. EIS measurements were performed every 10 min using a 20 mV p–p sinusoidal excitation signal. The adhesion over time was measured by using impedance changes (Zreal). SC5314 was used for the positive control and Filastatin treatments, and edt1 −/− is the negative control