Table 4 Linear relationship between the relative change of PT-INR and the difference in daptomycin concentrations between the trough and peak
Reagent | n | Unadjusted β (95% CI) (/μg/mL) | p value | r2 |
|---|---|---|---|---|
H0: β = 0 | ||||
1 | 34 | 5.1 × 10−4 (−9.2 × 10−4–1.9 × 10−3) | 0.48 | 0.02 |
2 | 34 | 2.2 × 10−3 (−5.6 × 10−4–4.9 × 10−3) | 0.12 | 0.15 |
3 | 34 | 3.1 × 10−3 (2.3 × 10−5–6.3 × 10−3) | 0.048 | 0.19 |
4 | 34 | 8.5 × 10−4 (−2.2 × 10−4–1.9 × 10−3) | 0.12 | 0.08 |
5 | 32 | −1.8 × 10−4 (−9.2 × 10−4–5.6 × 10−4) | 0.62 | 0.006 |
6 | 33 | 4.3 × 10−4 (−7.3 × 10−4–1.6 × 10−3) | 0.45 | 0.02 |
7 | 33 | −5.0 × 10−5 (−2.0 × 10−3–1.9 × 10−3) | 0.96 | <0.001 |
8 | 34 | −2.3 × 10−4 (−2.1 × 10−3–1.6 × 10−3) | 0.80 | 0.003 |
9 | 34 | 2.3 × 10−4 (−1.1 × 10−3–1.6 × 10−3) | 0.73 | 0.003 |