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Table 1 Characteristics of prothrombin time test reagents used in the study

From: Dose-dependent artificial prolongation of prothrombin time by interaction between daptomycin and test reagents in patients receiving warfarin: a prospective in vivo clinical study

No

Brand name

Manufacturer

Laboratory

ISI

Thromboplastin

Phospholipid

1

HemosIL Recombi PlasTin 2G

Instrumental Laboratories

University of Tokyo Hospital

1.01

Recombinant human tissue factor

Synthetic phospholipid

2

Neoplastin plus

Roche Diagnostics

Roche Diagnostics

1.33

Rabbit brain

Confidential

3

STA Neoplastin R

Roche Diagnostics

Roche Diagnostics

0.96

Recombinant human tissue factor

Confidential

4

Dade Innovin

Dade Behring (Sysmex)

Sysmex

1.0

Recombinant human tissue factor

No data

5

Thromborel S

Dade Behring (Sysmex)

Sysmex

1.0

Human placenta

No data

6

Thrombocheck PT

Sysmex

Sysmex

1.6

Rabbit brain

No data

7

Simplastin Excel S

BioMerieux

Kyowa Medex

1.22

Rabbit brain

No PG

8

Simplastin HTF

BioMerieux

Kyowa Medex

1.26

Cultured human lung cell

No PG

9

Coagupia PT–N

Sekisui Medical

Sekisui Medical

1.09

Rabbit brain

Confidential

  1. ISI international sensitivity index, PG phosphatidylglycerol