High fluoroquinolone MIC is associated with fluoroquinolone treatment failure in urinary tract infections caused by fluoroquinolone susceptible Escherichia coli

Table 1 Study definition of urinary tract infections (UTIs)

To be diagnosed of UTI, an eligible subject must meet both criterion 1 and criterion 2
Criterion 1	Having a positive urine culture ≥ 10⁵ cfu/mL, with no more than two species of microorganism
Criterion 2	At least one of the following
	ICD-9 code of signs and symptoms of UTIs
	Dipstick test positive for leukocyte esterase and/or nitrate
	Pyuria (≥ 10 white blood cells (wbc)/mm³ or ≥ 3 wbc/high power field of unspun urine)
	Physician diagnosis of a urinary tract infection (ICD-9 code)
	599.0 Urinary tract infection, site not specified
	590.x Infection of kidney
	595.0 Acute cystitis
	597.x Urethritis, not sexually transmitted diseases

ISSN: 1476-0711