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Table 2 Pulsotype, PBP genotypes and serotypes distribution of penicillin non-susceptible Streptococcus pneumoniae isolated from invasive diseases in Casablanca, Morocco (2007–2014)

From: Molecular characterization of penicillin non-susceptible Streptococcus pneumoniae isolated before and after pneumococcal conjugate vaccine implementation in Casablanca, Morocco

Pulsotypes Genotypes of pbp genes Number of strains MIC of PG (mg/L) Serotype (number of strains)
plp1a plp2b plp2x
Pre-vaccination period
A1, A2 1 5 1 3 1−2 14 (3)
A12 1 5 7 3 0.25−2 23F (2), 23A (1)
ND 1 5 7 1 1 5 (1)
A3 1 5 7 2 1 14 (2)
A4 2 8 1 2 0.5−2 19F (2)
A2 2 5 12 1 0.5 14 (1)
A11 4 2 2 3 0.5−1 24 (1) NT (2)
A9 4 2 2 1 0.5 19F (1)
A6, A5 4 2 5 8 0.125−0.5 19A (8)
A5 4 2 5 3 0.125−0.5 19A (3)
A7 4 2 5 5 0.125−0.5 19A (5)
A8 4 2 5 1 0.125 19F (1)
A10 6 3 3 2 0.125−0.25 6B (2)
Post-vaccination period
B8 1 5 1 2 2 14 (1)
B5, B6, B7 1 5 7 5 0.5−1 14 (5)
B1 2 8 1 1 0.5 19F (1)
B6 2 5 12 1 2 14 (1)
ND 4 2 2 3 0.25−0.5 NT (3)
B8 4 2 2 3 0.25−0.5 7F (1), 7A (2)
B3, B4 4 2 5 2 0.25 19A (2)
B2 6 3 3 2 0.125−1 6B (1), 6A (1)
  1. MIC minimal inhibitory concentration, PG penicillin G, pbp penicillin-binding protein gene, ND not determined