Table 2 Pulsotype, PBP genotypes and serotypes distribution of penicillin non-susceptible Streptococcus pneumoniae isolated from invasive diseases in Casablanca, Morocco (2007–2014)
Pulsotypes | Genotypes of pbp genes | Number of strains | MIC of PG (mg/L) | Serotype (number of strains) | ||
|---|---|---|---|---|---|---|
plp1a | plp2b | plp2x | ||||
Pre-vaccination period | ||||||
A1, A2 | 1 | 5 | 1 | 3 | 1−2 | 14 (3) |
A12 | 1 | 5 | 7 | 3 | 0.25−2 | 23F (2), 23A (1) |
ND | 1 | 5 | 7 | 1 | 1 | 5 (1) |
A3 | 1 | 5 | 7 | 2 | 1 | 14 (2) |
A4 | 2 | 8 | 1 | 2 | 0.5−2 | 19F (2) |
A2 | 2 | 5 | 12 | 1 | 0.5 | 14 (1) |
A11 | 4 | 2 | 2 | 3 | 0.5−1 | 24 (1) NT (2) |
A9 | 4 | 2 | 2 | 1 | 0.5 | 19F (1) |
A6, A5 | 4 | 2 | 5 | 8 | 0.125−0.5 | 19A (8) |
A5 | 4 | 2 | 5 | 3 | 0.125−0.5 | 19A (3) |
A7 | 4 | 2 | 5 | 5 | 0.125−0.5 | 19A (5) |
A8 | 4 | 2 | 5 | 1 | 0.125 | 19F (1) |
A10 | 6 | 3 | 3 | 2 | 0.125−0.25 | 6B (2) |
Post-vaccination period | ||||||
B8 | 1 | 5 | 1 | 2 | 2 | 14 (1) |
B5, B6, B7 | 1 | 5 | 7 | 5 | 0.5−1 | 14 (5) |
B1 | 2 | 8 | 1 | 1 | 0.5 | 19F (1) |
B6 | 2 | 5 | 12 | 1 | 2 | 14 (1) |
ND | 4 | 2 | 2 | 3 | 0.25−0.5 | NT (3) |
B8 | 4 | 2 | 2 | 3 | 0.25−0.5 | 7F (1), 7A (2) |
B3, B4 | 4 | 2 | 5 | 2 | 0.25 | 19A (2) |
B2 | 6 | 3 | 3 | 2 | 0.125−1 | 6B (1), 6A (1) |