Table 2 Comparison to other studies

Methods

Chart review of patients with positive smears from 2008 to 2014

Hospital records of babesiosis in NYS for 11 years (1982–1993)

Records of SBUH and VA^a hospitalized patients for 13 years with positive blood smears

Classified to have mild or severe (death, >2 weeks in hospital, ICU admission)

Controls with FUO^b, negative blood smears, matched by age and sex

Transferred from other hospital

27 (44%)

NA

30 (88%)

Median age (years)

64

66

46

Mean hospital stay (days)

9.6

11.7

12.7

ICU admission

20 (38%)

35 (25.2%)

–

Splenectomy

9 (15%)

16 (11.5%)

11 (32%)

Mean hemoglobin (g/dL)

10.6

11.3

10

Mean platelets (×10³/μL)

86

102

92

Mean LDH (U/L)

742

572

–

Mean ALT (U/L)

66

–

99

Mean AST (U/L)

85

–

121

Mean parasitemia (%)

3.4%

–

7.4%

Mean peak parasitemia (%)

4.4%

–

7.6%

Max parasitemia

25%

–

30%

Mean days of parasitemia

6

–

8.5

Treatment

Clindamycin 15 (24%)

Quinine 13 (21%)

Azithromycin 59 (95%)

Atovaquone 59 (95%)

Clindamycin 110 (79%)

Quinine 106 (76%)

Clindamycin 33 (97.1%)

Quinine 28 (82.3%)

Azithromycin 2 (5.9%)

Atovaquone 15 (44%)

Exchange transfusions

12 (19%)

6 (4.3%)

7 (20.6%)

Died

1 (2%)

9 (6.5%)

3 (8.8%)

Associations

High-grade parasitemia and:

 Malignancy

 Splenectomy

 LDH

 AST

 Total bilirubin

Severe disease and:

 Cardiac disease/murmur

 Splenectomy

 Alkaline phosphatase

 WBC

 Higher parasitemia

Complicated babesiosis and:

 Hemoglobin <10 g/dL

 Higher parasitemia