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Table 1 Values (median) of DOT and DDD in bloodstream infections treatment in microbiologically confirmed (LC) vs. unconfirmed cases (Not-LC)

From: Antibiotic consumption in laboratory confirmed vs. non-confirmed bloodstream infections among very low birth weight neonates in Poland

Antimicrobial group

DOT (days)

p value

DDD

p value

Microbiologically confirmed N = 649

Microbiologically unconfirmed N = 118

Microbiologically confirmed N = 649

Microbiologically unconfirmed N = 118

Median (IQR)

Median (IQR)

Median (IQR)

Median (IQR)

Aminoglycosides

7.0 (5.0; 9.3)

7.0 (6.0;7.0)

0.5265

0.101 (0.050; 0.171)

0.095 (0.045; 0.179)

<0.0001

Antimycotic

12.5 (9.0;16.0)

10.0 (7.8;14.3)

0.210 (0.132; 0.040)

0.198 (0.073; 0.463)

Beta-lactams

8.0 (5.0;11.0)

7.0 (6.8;8.8)

0.254 (0.136; 0.438)

0.300 (0.210; 0.420)

Glycopeptides

10.0 (8.0;11.0)

9.0 (7.0;11.0)

0.120 (0.080; 0.168)

0.120 (0.083; 0.146)

Other

9.0 (6.0;14.8)

8.0 (5.0;15.5)

0.210 (0.105; 0.530)

0.098 (0.060; 0.410)

Total

8.0 (5.0; 16.0)

7.0 (5.0; 15.5)

0.120 (0.050; 0.530)

0.143 (0.045; 0.463)

  1. DOT days of therapy (per one infection case), DDD defined daily dose (per one infection case), IQR interquartile range, N number of BSI cases