Occurrence of bla DHA-1 mediated cephalosporin resistance in Escherichia coli and their transcriptional response against cephalosporin stress: a report from India

Ingti, Birson; Paul, Deepjyoti; Maurya, Anand Prakash; Bora, Debajyoti; Chanda, Debadatta Dhar; Chakravarty, Atanu; Bhattacharjee, Amitabha

doi:10.1186/s12941-017-0189-x

Annals of Clinical Microbiology and Antimicrobials

Table 2 Clinical history, their molecular details and resistance profile of DHA-1 gene-positive E. coli isolates

From: Occurrence of bla _DHA-1 mediated cephalosporin resistance in Escherichia coli and their transcriptional response against cephalosporin stress: a report from India

Sl. No.	Sample ID	Age (years)	Sex	Ward/clinics	Type of clinical specimen	^aESBL genes detected	Carbapenemase genes detected	Other plasmid AmpC genes	(Inc type)	Resistance profile	MIC of β-lactam (mg/l)
Sl. No.	Sample ID	Age (years)	Sex	Ward/clinics	Type of clinical specimen	^aESBL genes detected	Carbapenemase genes detected	Other plasmid AmpC genes	(Inc type)	Resistance profile	CTX	CAZ	CRO	FEP	ATM	IMP	MEM	ETP
1	BM12	35	Male	Surgery	Pus	–	–	–	K	AMK, GEN, SXT	>512	>512	256	>512	64	16	8	8
2	BM26	107	Female	Pediatrics	Urine	TEM	–	–	FIA,	CIP, AMK, GEN, SXT	64	128	64	8	64	<2	<2	<2
3	BM59	55	Female	Medicine	Urine	–	–	–	FIA	CIP, AMK, GEN, SXT	128	64	64	16	128	<2	<2	<2
4	BM63	60	Female	Surgery	Pus	CTX-M	–	CIT	–	CIP, AMK, GEN, SXT	128	128	256	16	64	<2	<2	<2
5	BM130	27	Female	Surgery	Pus	TEM	–	CIT, EBC	HI1, L/M	CIP, AMK, GEN, SXT	>512	512	>512	64	256	16	4	4
6	BM138	45	Male	Surgery	Pus	CTX-M	–	–	–	CIP, GEN, SXT	64	128	128	32	128	<2	<2	<2
7	BM197	30	Female	Surgery	Pus	–	–	CIT	L/M	CIP, AMK, GEN, SXT	512	>512	256	64	512	2	<2	<2
8	BM230	43	Female	Surgery	Pus	CTX-M, SHV	–	CIT	L/M	CIP, AMK, GEN, SXT	64	128	256	32	256	16	8	16
9	BM252	7	Female	Paediatrics	Urine	SHV	–	CIT, EBC	F1B, FIA	CIP, AMK, GEN, SXT	>512	>512	>512	128	256	8	<2	<2
10	BM355	10	Male	Paediatrics	Urine	–	NDM	CIT	FIA	CIP, AMK, SXT	>512	512	>512	8	256	<2	<2	<2
11	BM409	61	Male	Medicine	Urine	CTX-M	–	CIT	K	CIP, AMK, GEN, SXT	64	64	32	16	128	<2	<2	<2
12	BM441	40	Male	Medicine	Stool	CTX-M, SHV	–	–	FIA	CIP, AMK, GEN, SXT	32	64	128	32	256	<2	<2	<2
13	BM508	48	Male	Surgery	Pus	–	–	CIT	I1	CIP, AMK, GEN	32	32	32	16	256	<2	<2	<2
14	BM520	55	Female	Surgery	Pus	OXA-10, SHV	–	–	–	CIP, GEN, SXT	16	128	128	32	32	<2	<2	<2
15	BM567	30	Male	Medicine	Urine	–	–	–	–	CIP, AMK, GEN, SXT	128	256	256	32	256	<2	<2	<2
16	BM576	40	Female	Medicine	Urine	CTX-M, TEM	–	CIT	K, B/O	AMK, GEN, SXT	>512	>512	>512	128	>512	16	16	32

AMK amikacin; GEN gentamycin; CIP ciprofloxacin; SXT cottrimoxazole; CTX cefotaxime; CAZ ceftazidime; CRO ceftriaxone; FEP cefepime; ATM aztreonam; IMP imipenem; MEM meropenem; ETP ertapenem
^aExtended spectrum β-lactamase

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ISSN: 1476-0711

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