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Table 2 Molecular characterization of antimicrobial resistance genotypes among APEC isolates

From: Genetic elements associated with antimicrobial resistance among avian pathogenic Escherichia coli

Antibiotic

Antimicrobial class

Number of resistance isolates

Associated genes tested

Number of positive isolates

Ampicillin

Penicillins

116 (100%)

bla TEM

102

bla SHV

0

bla oxa1

14

Chloramphenicol

Phenicols

98 (84.5%)

cat1

86

cat2

4

cat3

0

cmlA

8

cmlB

0

Streptomycin

Aminoglycosides

58 (50%)

strA-strB

34

Ciprofloxacin

Quinolones

48 (41.4%)

PMQRa

 

qnrA

10

qnrB

4

qnrS

2

qnrD

0

aac (6′)-Ib-cr

0

QRDRb

 

S83L

(gyrA)

27

S83L + D87 N

(gyrA)

4

S80I

(pyrC)

1

Sulfamethoxazole-trimethoprim

Potentiated sulfonamides

68 (58.6%)

sul1

23

sul2

39

sul3

0

Tetracycline

Tetracyclines

108 (93.1%)

tetA

50

tetB

54

tetC

0

tetD

0

tetE

0

tetG

0

tetA + tetB

4

Kanamycin

Aminoglycosides

80 (69.0%)

aphA1

65

aphA2

11

aphA1 + aphA2

4

Cefotaxime (ESβL)

Cephalosporins

68 (58.6%)

CTX-M (group 1)

15

CTX-M (group 2)

0

CTX-M (group 8)

0

CTX-M (group 9)

2

CTX-M (group 25)

0

bla TEM

20

bla SHV

0

bla oxa1

7

CTX-M (group 1) + bla TEM

24

  1. aPlasmid-mediated quinolone resistance
  2. bQuinolone resistance determining region