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Table 3 In-vitro screening of traditionally used anti-leishmanial and anti-malarial plants against Leishmania and Plasmodia parasites

From: Ethnomedicines and anti-parasitic activities of Pakistani medicinal plants against Plasmodia and Leishmania parasites

Plant name Part used Parasite type Extract Concentration (µg/ml) Inhibition (%) Citation
Aloe vera Leaves Leishmania tropica Crude methanol 25 15 [25]
50 27
75 43
100 66
Artemisia annua Leaves Plasmodium falciparum Aqueous 0.095 50 [86]
Azadiracha indica Leaves Plasmodium falciparum Ethanol 2.4 50 [36]
2.5 50
Asparagus asiaticus Roots Leishmania major Crude methanol 25 22 [63]
50 34
250 42
500 51
Amphotericin B
(Reference drug as a control)
25 50
50 75
250 88
500 100
Citrullus colocynthis Fruits Leishmania major Crude methanol 25 67 [35]
50 71
250 88
500 100
Juniperus excels Fresh berries Leishmania major Crude methanol 25 49 [37]
50 58
250 88
500 97
Melia azedarach Fruit Leishmania tropica Aqueous 1500 55.9 [86]
2500 67.4
5000 80.4
Moringa oleifera Leaves Plasmodium falciparum Acetone 400 59.8 [31]
Nepeta praetervisa Leaves Leishmania major Methanol 25 39 [62]
50 54
250 68
500 78
Peganum harmala Seeds Plasmodium falciparum Ethanol 12.5 91 [58]
25 97.4
50 98.5
100 99.8
Chloroquine NA 99.6
Perotis hordeiformis Leaves Leishmania major Methanol 25 47 [65]
50 58
250 70
500 80
Amphotericin B
(Reference drug as a control)
25 50
50 75
250 88
500 100
Rhazya stricta Leaves Leishmania major Crude methanol 25 65 [34]
50 70
250 92
500 100
Salvia bucharica Leaves Leishmania major Crude methanol 25 44 [67]
50 40
250 59
500 75
Tamarix aphylla Barks Leishmania tropica Crude methanol 25 20 [25]
50 28
75 54
100 84
Thuspeinanta brahuica Leaves Leishmania major Crude methanol 25 40 [87]
50 58
75 70
100 82
Amphotericin B (Reference drug as a control) 25 50
50 75
75 88
100 100