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Table 4 Sensitivity, specificity, negative predictive value, positive predictive value of MEM-MHT, ERT-MHT and correlation with OXA-48 gene positivity

From: Phenotypic and genotypic characteristics of carbapenem-resistant Enterobacteriaceae in a tertiary-level reference hospital in Turkey

  

Sensitivity  %

Specificity  %

NPV  %

PPV  %

Correlation with OXA-48 gene positivity

All OXA-48 positive isolates

MEM-MHT

70.9

88.7

66.3

90.7

p < 0.001

ERT-MHT

70.6

87.5

66.3

89.5

p < 0.001

OXA-48 positive K. pneumoniae

MEM-MHT

89.3

84.6

64.7

96.2

p < 0.001

ERT-MHT

92.7

92.9

76.5

98.1

p < 0.001

OXA-48 positive S. marcescens

MEM-MHT

20

86.9

71.4

40

p > 0.05

ERT-MHT

16.7

85.2

82.1

20

p > 0.05

OXA-48 positive M. morganii

MEM-MHT

37.5

100

64.3

100

p > 0.05

ERT-MHT

33.3

100

57.1

100

p > 0.05

OXA-48 positive P. mirabilis

MEM-MHT

44.4

75

54.6

66.7

p > 0.05

ERT-MHT

40

71.4

45.5

66.7

p > 0.05

OXA-48 positive E. coli

MEM-MHT

100

100

100

100

p < 0.001

ERT-MHT

80

100

60

100

p < 0.05

OXA-48 positive E. cloacae

MEM-MHT

37.5

100

50

100

p > 0.05

ERT-MHT

37.5

100

50

100

p > 0.05

OXA-48 positive E. aerogenes

MEM-MHT

71.43

100

60

100

p > 0.05

ERT-MHT

71.43

100

60

100

p > 0.05

  1. MEM-MHT modified Hodge test with meropenem, ERT-MHT modified Hodge test with ertapenem, NPV negative predictive value, PPV positive predictive value