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Table 2 Susceptibilities of S.aureus to various antibiotics and the concordance and kappa statistics between CLSI 2015 and EUCAST 2015 guidelines

From: Comparison of Clinical Laboratory Standards Institute and European Committee on Antimicrobial Susceptibility Testing guidelines for the interpretation of antibiotic susceptibility at a University teaching hospital in Nairobi, Kenya: a cross-sectional study

Antibiotic

CLSI (%); n = 1103

EUCAST (%); n = 1103

Concordance (%)

Kappa, κ (95 % CI)

S

I

R

S

I

R

Penicillin

10.6

0

89.4

10.6

0

89.4

100

1

TMP/SMX

0

0

100

0

0

100

100

1

Clindamycin

98.0

0.3

1.7

98.0

0.1

1.9

99.5

0.904 (0.826, 0.982)

Erythromycin

85.6

0.5

13.9

86.0

0

14.0

99.4

0.978 (0.960, 0.996)

Gentamicin

96.3

0.5

3.2

91.5

0

8.5

94.6

0.537 (0.441, 0.633)

Levofloxacin

90.8

0.3

8.9

90.8

0.3

8.9

100

1

Linezolid

100

0

0

100

0

0

100

1

Oxacillin

93.3

0

6.7

93.3

0

6.7

100

1

Tetracycline

83.2

0.1

16.7

82.4

0.8

16.8

98.9

0.962 (0.940, 0.984)

Vancomycin

100

0

0

100

0

0

100

1

  1. TMP/SMX trimethoprim–sulfamethoxazole, S susceptible, I intermediate, R resistant