Table 1 Susceptibilities of E. coli to various antibiotics, concordance and kappa statistics between CLSI 2015 and EUCAST 2015 guidelines
Antibiotic | CLSI (%); n = 5165 | EUCAST (%); n = 5165 | Concordance (%) | Kappa, κ (95 % CI) | ||||
|---|---|---|---|---|---|---|---|---|
S | I | R | S | I | R | |||
Ampicillin | 13.8 | 0.5 | 85.7 | 13.8 | 0 | 86.2 | 99.5 | 0.985 (0.979, 0.991) |
Amox-Clav | 55.8 | 23.8 | 20.4 | 55.8 | 0 | 44.2 | 78.2 | 0.581 (0.567, 0.595) |
TMP/SMX | 0 | 0 | 100 | 0 | 0 | 100 | 100 | 1 |
Nitrofurantoin | 84.6 | 11.9 | 3.5 | 96.5 | 0 | 3.5 | 87.6 | 0.351 (0.314, 0.388) |
Ciprofloxacin | 57.3 | 0.2 | 42.5 | 55.9 | 1.4 | 42.7 | 98.4 | 0.969 (0.963, 0.975) |
Cefuroxime | 63.7 | 3.5 | 32.8 | 63.7 | 0 | 36.3 | 96.5 | 0.924 (0.914, 0.934) |
Gentamicin | 78.5 | 0.2 | 21.3 | 78.1 | 0.4 | 21.5 | 99.5 | 0.979 (0.973, 0.985) |
Amikacin | 99.3 | 0.3 | 0.4 | 90.5 | 8.8 | 0.7 | 91.1 | 0.112 (0.079, 0.145) |
Cefotaxime | 69.7 | 0.4 | 29.9 | 69.7 | 0.4 | 29.9 | 100 | 1 |
Ceftazidime | 76.3 | 0.9 | 22.8 | 71.5 | 4.8 | 23.7 | 93.7 | 0.859 (0.843, 0.85) |
Ceftriaxone | 67.7 | 0.1 | 32.2 | 67.7 | 0.1 | 32.2 | 100 | 1 |
Cefepime | 80.5 | 10.0 | 9.5 | 72.9 | 9.8 | 17.3 | 84.9 | 0.600 (0.578, 0.622) |
Meropenem | 99.7 | 0.1 | 0.2 | 99.8 | 0.1 | 0.1 | 99.7 | 0.724 (0.573, 0.875) |