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Table 1 Phenotypic and molecular characterization results of IRMS and MRIS P. aeruginosa isolates

From: Characterization of Pseudomonas aeruginosa with discrepant carbapenem susceptibility profile

Micro No. Imipenem MIC
(µg/ml)
Meropenem MIC
(µg/ml)
Doripenem MIC
(µg/ml)
CarbaNP test MHT Multiple × PCRa oprD mutations RT-qPCR oprD
(fold difference)
RT-qPCR
mexAB
(fold difference)
Sequence
Types-ST
(MLST)
Imipenem resistant meropenem susceptible P. aeruginosa (IRMS)  
 PA3970 4 4 4 Negative Negative Negative L4, L6 2.31
 PA5778 6 1.5 1 Negative Negative Negative L4, L6 0.81 ST 1685
 PA4745 >32 4 2 Negative Negative Negative L2, L7, L8, L9, L15 Undetermined
 PA6192 4 2 0.5 Negative Negative Negative L2, L7, L8, L9, L15 0.16 ST 1993
 PA6362 4 1 1 Negative Negative Negative L4, L6 1.27 ST 360
 PA6475 32 2 1.5 Negative Negative Negative Mutations in primer binding site Undetermined ST 1952
 PA6476 4 1 1 Negative Negative Negative L2, L7, L8,
L9, L15
0.39 ST 617
Meropenem resistant imipenem susceptible P. aeruginosa (MRIS)  
 PA4381 6 4 3 Negative Negative Negative Not done Not done 3.37
 PA5350 4 32 4 Negative Negative Negative Not done Not done 2.54
 PA26815 3 8 12 Negative Negative Negative Not done Not done 1.09
  1. Genes tested: blaIMP,blaVIM, blaNDM, blaKPC, blaOXA-48 like genes. Relative quantification of oprD and mexAB expression was normalized with ATCC 27853 P. aeruginosa with a value of 1.0 and the fold difference was mentioned above