Spectrum adequacy of antibiotic regimens for secondary peritonitis: a retrospective analysis in intermediate and intensive care unit patients

Table 4 Spectrum adequacy of selected antimicrobial regimens in patients presenting with secondary peritonitis (88 community acquired cases, c.a.; 154 postoperative cases, p.op.)

	TZP		TZP + GEN		TZP + VAN		TZP + LZD
	c.a.	p.op.	c.a.	p.op.	c.a.	p.op.	c.a.	p.op.
Enterobacteriaceae
%S	86.4	69.5	97.7	96.8
%R	5.7	18.2	0	0
Enterobacteriaceae plus enterococci
%S	72.7	58.4	84.1	75.3	85.2	67.5	85.2	69.5
%R	18.2	33.8	12.5	21.4	6.8	22.1	6.8	18.2

	CTX		CTX + GEN		CTX + VAN		CTX + LZD
	c.a.	p.op.	c.a.	p.op.	c.a.	p.op.	c.a.	p.op.
Enterobacteriaceae
%S	95.5	83.8	98.9	97.4
%R	2.3	11.7	1.1	1.3
Enterobacteriaceae plus enterococci
%S	62.5	41.6	65.9	43.5	93.2	77.9	94.3	83.1
%R	35.2	57.1	34.1	55.2	4.5	16.9	3.4	12.3

	MEM				MEM + VAN		MEM + LZD
	c.a.	p.op.	c.a.	p.op.	c.a.	p.op.	c.a.	p.op.
Enterobacteriaceae
%S	100	100
%R	0	0
Enterobacteriaceae plus enterococci
%S	87.5	78.6			98.9	94.2	98.9	99.4
%R	12.5	20.8			1.1	5.8	1.1	0.6

	CIP				CIP + VAN		CIP + LZD
	c.a.	p.op.	c.a.	p.op.	c.a.	p.op.	c.a.	p.op.
Enterobacteriaceae
%S	93.2	87.7
%R	5.7	9.7
Enterobacteriaceae plus enterococci
%S	63.6	39.6			90.9	80.5	92.0	87.0
%R	12.5	37.0			5.7	13.0	5.7	10.4

	TGC		TGC + GEN		TGC + CIP		TGC + CTX
	c.a.	p.op.	c.a.	p.op.	c.a.	p.op.	c.a.	p.op.
Enterobacteriaceae
%S	84.1	83.1	97.7	99.4	98.9	98.7	98.9	92.2
%R	11.4	13.0	1.1	0.6	0	0.6	0	1.9
Enterobacteriaceae plus enterococci
%S	84.1	83.1	97.7	99.4	98.9	98.7	98.9	92.2
%R	11.4	13.0	1.1	0.6	0	0.6	0	1.9

%S: all pathogens of the respective categories are susceptible to the tested antimicrobial regimen, or no pathogen of the respective categories was isolated. %R: at least one pathogen of the respective categories is resistant to all agents of the tested regimen. Missing to 100 %: no full, but intermediate or unknown susceptibility of at least one pathogen to at least one agent

ISSN: 1476-0711