The spread of bla OXA-48 and bla OXA-244 carbapenemase genes among Klebsiella pneumoniae, Proteus mirabilis and Enterobacter spp. isolated in Moscow, Russia

Table 2 Donor, recipient and transconjugant K. pneumoniae and E. coli strains features at intra- and inter-species conjugation

Role at conjugation	Strain	Conjugation effectiveness	Genetic markers								Plasmids
Role at conjugation	Strain	Conjugation effectiveness	repA	traU	bla _OXA-244	bla _CTX-M	bla _TEM	bla _SHV	int1	ompK36	Plasmids
Donor	K. pneumoniae B-500		+	+	+	+	+	+	+	+	L/M, UP
Donor	K. pneumoniae B-757 K		+	+	+	+	+	+	+	+	L/M, UP
Recipient	K. pneumoniae 9 Rif		−	−	−	−	−	+	−	+	−
Recipient	E. coli HB-101 Rif		−	−	−	−	−	−	−	−	−
Transconjugant	K. pneumoniae 9/500-1	2.0 × 10⁻⁴	+	+	+	+	+	+	+	+	L/M, UP
Transconjugant	K. pneumoniae 9/500-2	2.0 × 10⁻⁴	−	−	−	+	+	+	+	+	UP
Transconjugant	E. coli HB/500-1	2.0 × 10⁻³	+	+	+	−	−	−	−	−	L/M
Transconjugant	K. pneumoniae 9/757-1	8.5 × 10⁻⁴	+	+	+	+	+	+	+	+	L/M, UP
Transconjugant	K. pneumoniae 9/757-2	8.5 × 10⁻⁴	−	−	−	+	+	+	+	+	UP
Transconjugant	E. coli HB/757-1	3.0 × 10⁻³	+	+	+	−	−	−	−	−	L/M

repA, traU genetic markers of the IncL/M plasmid, bla _OXA-244, bla _CTX-M, bla _TEM, bla _SHV beta-lactamase genes, int1 class 1 integrase gene, ompK36 K. pneumoniae porin protein gene, «+» positive, «−» negative, L/M conjugative plasmid IncL/M, UP unidentified conjugative plasmid

ISSN: 1476-0711