Table 5 Phage-based reduction of biofilms, with or without using adjuvant chemical, in PIA and FnBPA types of both MRSA and SA
Bacteria | Type of biofilm | Phage application without chemical adjuvant | Phage application with chemical adjuvant |
|---|---|---|---|
Level of biofilm before: after (score of reduction) | Level of biofilm before: after (score of reduction) | ||
SA-1 | PIA | High: high (0) | High: weak (2) |
SA-2 | PIA | Mod: weak (1) | Mod: zero (2) |
SA-3 | PIA | weak: zero (1) | weak: zero (1) |
SA-10 | PIA | weak: zero (1) | weak: zero (1) |
SA-5 | PIA | High: High (0) | High: weak (2) |
SA-6 | PIA | weak: zero (1) | weak: zero (1) |
ATCC 11987 | PIA | Mod: weak (1) | Mod: weak (1) |
SA-8 | PIA | weak: zero (1) | weak: zero (1) |
Average score of reduction | 0.75 | 1.38 | |
SA-9 | FnBPA | Mod: Mod (0) | Mod: zero (2) |
SA-4 | FnBPA | High: high (0) | High: weak (2) |
SA-7 | FnBPA | weak: weak (0) | weak: zero (1) |
ATCC 27691 | FnBPA | weak: zero (1) | weak: zero (1) |
Average score of reduction | 0.25 | 1.5 | |
MR-4 | PIA | Mod: Mod (0) | Mod: zero (2) |
MR-5 | PIA | High: High (0) | High: weak (2) |
MR-7 | PIA | weak: zero (1) | weak: zero (1) |
Average score of reduction | 0.33 | 1.67 | |
MR-1 | FnBPA | High: high (0) | High: zero (3) |
MR-2 | FnBPA | Mod: mod (0) | Mod: weak (1) |
MR-3 | FnBPA | High: high (0) | High: weak (2) |
MR-6 | FnBPA | weak: zero (1) | weak: zero (1) |
ATCC 700699 | FnBPA | Mod: Mod (0) | Mod: zero (2) |
ATCC 43300 | FnBPA | High: high (0) | High: mod (1) |
Average score of reduction | 0.17 | 1.67 | |