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TableĀ 5 Phage-based reduction of biofilms, with or without using adjuvant chemical, in PIA and FnBPA types of both MRSA and SA

From: The potential of bacteriophage cocktail in eliminating Methicillin-resistant Staphylococcus aureus biofilms in terms of different extracellular matrices expressed by PIA, ciaA-D and FnBPA genes

Bacteria Type of biofilm Phage application without chemical adjuvant Phage application with chemical adjuvant
Level of biofilm before: after (score of reduction) Level of biofilm before: after (score of reduction)
SA-1 PIA High: high (0) High: weak (2)
SA-2 PIA Mod: weak (1) Mod: zero (2)
SA-3 PIA weak: zero (1) weak: zero (1)
SA-10 PIA weak: zero (1) weak: zero (1)
SA-5 PIA High: High (0) High: weak (2)
SA-6 PIA weak: zero (1) weak: zero (1)
ATCC 11987 PIA Mod: weak (1) Mod: weak (1)
SA-8 PIA weak: zero (1) weak: zero (1)
Average score of reduction 0.75 1.38
SA-9 FnBPA Mod: Mod (0) Mod: zero (2)
SA-4 FnBPA High: high (0) High: weak (2)
SA-7 FnBPA weak: weak (0) weak: zero (1)
ATCC 27691 FnBPA weak: zero (1) weak: zero (1)
Average score of reduction 0.25 1.5
MR-4 PIA Mod: Mod (0) Mod: zero (2)
MR-5 PIA High: High (0) High: weak (2)
MR-7 PIA weak: zero (1) weak: zero (1)
Average score of reduction 0.33 1.67
MR-1 FnBPA High: high (0) High: zero (3)
MR-2 FnBPA Mod: mod (0) Mod: weak (1)
MR-3 FnBPA High: high (0) High: weak (2)
MR-6 FnBPA weak: zero (1) weak: zero (1)
ATCC 700699 FnBPA Mod: Mod (0) Mod: zero (2)
ATCC 43300 FnBPA High: high (0) High: mod (1)
Average score of reduction 0.17 1.67
  1. Mod represents moderate production of biofilms, Zero describes mean OD values of TCP method less than 0.01