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Table 1 Antimicrobial activity of methanolic extracts of R. californica and U. californica analyzed by Kirby-Bauer disc-diffusion assay

From: Antibacterial activity of native California medicinal plant extracts isolated from Rhamnus californica and Umbellularia californica

Bacterial Strains

Diameter of Zone of Inhibition (mm)

Plants

Dose (mg)

B. cereus ATCC® 14579

E. coli ATCC® 25922

P. aeruginosa ATCC® 10145

S. aureus ATCC® 25923

MRSA 1 ATCC® BAA-1683

S. pyogenes 1 ATCC® 10782

R. californica

       

Leaves

1

10.0 ± 2.1

--

--

--

10.0

9.0

 

5

12.3 ± 0.5

--

--

11.0 ± 1.2**

15.0

12.0

 

10

13.0 ± 0.0

--

--

12.5 ± 2.1Ψ

16.0

14.0

 

25

14.3 ± 0.5

--

--

14.0 ± 1.4**

n.t.

n.t.

U. californica

       

Leaves

1

9.0 ± 0.0

--

--

--

8.0

8.0

 

5

9.5 ± 0.5

--

--

9.3 ± 1.0**

9.0

11.0

 

10

9.3 ± 0.5

--

--

10.5 ± 1.4Ψ

10.0

15.0

 

25

10.0 ± 0.0

--

--

10.9 ± 2.0**

n.t.

n.t.

Bark

1

--

--

--

8.0 ± 0.0Ψ

--

--

 

5

9.3 ± 0.5

--

--

12.8 ± 2.6**

9.0

8.0

 

10

10.3 ± 0.5

--

--

17.5 ± 1.4Ψ

10.0

11.0

 

25

11.7 ± 0.5

--

--

16.0 ± 1.2**

n.t.

n.t.

Streptomycin

0.01

23.8 ± 1.2

19.8 ± 0.2

10.4 ± 0.3

18.9 ± 1.0

17.0 ± 0.0

18.0 ± 0.0

Methanol

100 %

--

--

--

--

--

--

  1. Data represented as averages ± SD. --, no significant zone of inhibition; n.t., not tested; 1, n = 1; Ψ, n = 2; **, n = 4; remaining data (B. cereus, E. coli, and P. aeruginosa) represent sample size of 3 (n = 3)