Novel approach of using a cocktail of designed bacteriophages against gut pathogenic E. colifor bacterial load biocontrol

Table 1 Mean LR (log ₁₀ CFU/ml) of fecal output of E. coli in rat animals treated with different concentrations of phage master mix in drinking water

Phage concentration PFU/ml in drinking water	Mean LR (log₁₀CFU/ml)
Phage concentration PFU/ml in drinking water	2 days	4 days
1x10³	0 ± 0.0	1.2 ± 0.08
1x10⁴	0.1 ± 0.02	1.2 ± 0.1
1x10⁵	0.3 ± 0.06	1.41 ± 0.17
1x10⁶	0.28 ± 0.07	1.36 ± 0.07
1x10⁷(optimal)	0.6 ± 0.04	1.8 ± 0.14
1x10⁸	0.6 ± 0.08	1.73 ± 0.2
1x10⁹	0.5 ± 0.04	1.7 ± 0.15
1x10¹⁰	0.4 ± 0.09	1.5 ± 0.2

ISSN: 1476-0711