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Table 3 Frequency of mutation with hydroxychavicol

From: In vitro antifungal activity of hydroxychavicol isolated from Piper betle L

Tested strains

Mutation frequency with hydroxychavicol at:

 

2 × MIC

4 × MIC

8 × MIC

C. albicans ATCC 90028

2.5 × 109

<109

<109

C. tropicalis ATCC 750

2 × 109

<109

<109

C. glabrata ATCC 90030

1.5 × 109

1.5 × 109

<109

C. parapsilosis ATCC 22019

2 × 109

2 × 109

<109

A. fumigatus MTCC 1811

<109

<109

<109

A. flavus MTCC 1973

<109

<109

<109

  1. MIC of hydroxychavicol is 31.25 μg/ml for C. glabrata and C. parapsilosis while as 250 μg/ml for other species tested.
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Annals of Clinical Microbiology and Antimicrobials

ISSN: 1476-0711

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