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Table 1 Minimal inhibitory concentrations (MIC) compounds isolated from Schinus terebinthifolius against different isolates of Paraccocidioides brasiliensis (values in μg/ml).

From: Antifungal activity of schinol and a new biphenyl compound isolated from Schinus terebinthifolius against the pathogenic fungus Paracoccidioides brasiliensis

 

Pb18

Pb01

Pb3

PbB339

Pb1578

Compound 1

62.5

125

31.2

15.6

7.5

Compound 2

250

125

250

15.6

250

Compound 3

≥250

≥250

≥250

≥250

≥250

Compound 4

≥250

≥250

≥250

≥250

≥250

Amphotericin B*

0.0062

0.12

0.015

0.0062

0.0062

Trimethoprim-sulfamethoxazol*

300

300

300

75

75

  1. Compound 1: schinol; compound 2: 4'-ethyl-4-methyl-2,2',6,6'-tetrahydroxy[1,1'-biphenyl]-4,4'-dicarboxylate; compound 3: quercetin; and compound 4: kaempferol. The concentrations of 25-0.03 μg/ml for used for amphotericin B and 600-1.17 μg/ml for SMT/TMP