Figure 3
From: Infected foot ulcers in male and female diabetic patients: a clinico-bioinformative study
(a) CTX-M-15 enzyme modeled from the bla CTX-M-15 gene sequence [Genbank: FJ997866] of E. coli strain D253. The active site Ω-loop, the SDN loop and the KTG motif are labeled. A = 91.5%, B = 7.8%, C = 0.7%, D = 0.0%, where 'A', 'B', 'C' and 'D' stand for percent amino acid residues in most favored, additional allowed, generously allowed and disallowed regions of the Ramachandran plot respectively. The z-score for the modeled structure was equal to 0.027. (b) Amino acid residues crucial to the interaction between cefotaxime and CTX-M-15.