Skip to main content

Advertisement

Table 1 Susceptibility pattern of 53 imipenem-non-susceptible Acinetobacter baumanni i strains to 12 antimicrobial agents

From: Dissemination of multidrug resistant Acinetobacter baumannii in various hospitals of Antananarivo Madagascar

Antimicrobial Disk Diffusion        
  Disc content Zone diameters* (mm) Equivalent MICs breakpoints * (mg/l) Results of disk diffusion n (%)
   S R S R S I R
Amikacin 30 μg ≥17 <15 ≤8 >16 25 (47,2) 1 (1,9) 27 (50,9)
Tobramycin 10 μg ≥16 <16 ≤4 >4 36 (67,9) 0 17 (32,1)
Gentamycin 15 μg ≥16 <16 ≤4 >4 1 (1,9) 0 52 (98,1)
Ampicillin/Sulbactam‡ 10 μg/10 μg ≥15 ≤11 ≤8/4 ≥32/16 42 (79.2) 0 11 (20.8)
Ticarcillin/clavulanic acid 75/10 μg ≥22 <18 ≤16/2 >64/2 1 (1,9) 0 52 (98,1)
Piperacilin-Tazobactam 75/10 μg ≥19 <14 ≤16/4 >64/4 0 1 (1,9) 52 (98,1)
Ceftazidime 30 μg ≥21 <19 ≤4 >8 3 (5,7) 0 50 (94,3)
Ciprofloxacin 5 μg ≥22 <19 ≤1 >2 1 (1,9) 0 52 (98,1)
Sulfamethoxazole/trimethoprim 23.75/1.25 μg ≥16 <13 ≤38/2 >76/4 0 0 53 (100)
Imipenem 10 μg ≥24 <17 ≤2 >8 0 4 (7.5) 49 (92.5)
Colistin 50 μg ≥15 <15 ≤2 >2 53 (100) 0 0
  MICs    S R MIC50 (mg/l) MIC 90 (mg/l)
Imipenem     ≤2 >8 32   32
Meropenem     ≤2 >8 ≥32   ≥32
  1. *: According to the Antibiogram Committee of the French Microbiology Society except for Ampicillin/sulbactam
  2. ‡: According to the Clinical and Laboratory Standards Institute
  3. S: susceptible; I: intermediate; R: resistant.