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Table 1 Susceptibility pattern of 53 imipenem-non-susceptible Acinetobacter baumanni i strains to 12 antimicrobial agents

From: Dissemination of multidrug resistant Acinetobacter baumannii in various hospitals of Antananarivo Madagascar

Antimicrobial

Disk Diffusion

       
 

Disc content

Zone diameters* (mm)

Equivalent MICs breakpoints * (mg/l)

Results of disk diffusion n (%)

  

S

R

S

R

S

I

R

Amikacin

30 μg

≥17

<15

≤8

>16

25 (47,2)

1 (1,9)

27 (50,9)

Tobramycin

10 μg

≥16

<16

≤4

>4

36 (67,9)

0

17 (32,1)

Gentamycin

15 μg

≥16

<16

≤4

>4

1 (1,9)

0

52 (98,1)

Ampicillin/Sulbactam‡

10 μg/10 μg

≥15

≤11

≤8/4

≥32/16

42 (79.2)

0

11 (20.8)

Ticarcillin/clavulanic acid

75/10 μg

≥22

<18

≤16/2

>64/2

1 (1,9)

0

52 (98,1)

Piperacilin-Tazobactam

75/10 μg

≥19

<14

≤16/4

>64/4

0

1 (1,9)

52 (98,1)

Ceftazidime

30 μg

≥21

<19

≤4

>8

3 (5,7)

0

50 (94,3)

Ciprofloxacin

5 μg

≥22

<19

≤1

>2

1 (1,9)

0

52 (98,1)

Sulfamethoxazole/trimethoprim

23.75/1.25 μg

≥16

<13

≤38/2

>76/4

0

0

53 (100)

Imipenem

10 μg

≥24

<17

≤2

>8

0

4 (7.5)

49 (92.5)

Colistin

50 μg

≥15

<15

≤2

>2

53 (100)

0

0

 

MICs

  

S

R

MIC50 (mg/l) MIC 90 (mg/l)

Imipenem

   

≤2

>8

32

 

32

Meropenem

   

≤2

>8

≥32

 

≥32

  1. *: According to the Antibiogram Committee of the French Microbiology Society except for Ampicillin/sulbactam
  2. ‡: According to the Clinical and Laboratory Standards Institute
  3. S: susceptible; I: intermediate; R: resistant.