Antibiotic susceptibility of coagulase-negative staphylococci isolated from very low birth weight babies: comprehensive comparisons of bacteria at different stages of biofilm formation

Table 4 No. of CoNS isolates showing reduction^a or enhancement when biofilms/adherent cells exposed to antibiotics.

Effect	Number (%) of isolates affected by
	Gentamicin (GEN)	Oxacillin (OXA)	Vancomycin (VAN)	GEN, OXA, VAN
Reduction	2 (8)	7 (29)	14 (64)	14 (64)
Enhancement	0 (0)	2 (8)	0 (0)	0 (0)
None	22 (92)	15 (63)	10 (36)	10 (36)

^a After overnight antibiotic exposure, the difference in OD₆₀₀ values between test biofilms and antibiotic-free wells, if greater than intra-microplate variability, were defined as significant; a decrease was considered a reduction and an increase was considered an enhancement.

ISSN: 1476-0711