Table 1 Anti-cryptococcal activity of subfraction F2.4 from Stryphnodendron adstringens against strains of Cryptococcus neoformans with different capsule expressions: T1-444 strain, ATCC 28957 strain and an acapsular mutant (Cap 67 strain).
Drugs | C. neoformans T1-444 | C. neoformans ATCC 28957 | C. neoformans Cap67 | |||
|---|---|---|---|---|---|---|
MIC | MFC | MIC | MFC | MIC | MFC | |
Subfraction F2.4 | 5 | >160 | 5 | >160 | 2.5 | 20 |
Fluconazole | 4 | 16 | 2 | 8 | 2 | 8 |
Itraconazole | 0.12 | 8 | 0.12 | 8 | 0.03 | 8 |
Amphotericin B | 0.12 | 0.25 | 0.06 | 0.25 | 0.06 | 0.12 |